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Effects of Ocean Acidification on the Photosynthetic Ability of Chaetoceros gracilis in the Monterey Bay

Harvell et al. | Jan 16, 2020

Effects of Ocean Acidification on the Photosynthetic Ability of <i>Chaetoceros gracilis</i> in the Monterey Bay

In this article, Harvell and Nicholson hypothesized that increased ocean acidity would decrease the photosynthetic ability of Chaetoceros gracilis, a diatom prolific in Monterey Bay, because of the usually corrosive effects of carbonic acid on both seashells and cells’ internal structures. They altered pH of algae environments and measured the photosynthetic ability of diatoms over four days by spectrophotometer. Overall, their findings indicate that C. gracilis may become more abundant in Monterey Bay as the pH of the ocean continues to drop, potentially contributing to harmful algal blooms.

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Inhibiting the ERK pathway and the TRPM7 ion channel in gastric and bladder cancer cells

Yang et al. | Oct 14, 2021

Inhibiting the ERK pathway and the TRPM7 ion channel in gastric and bladder cancer cells

In this work the authors investigate new possible treatment methods for gastric and bladder cancers. They specifically targeted the transient receptor potential cation subfamily M member 7 (TRPM7), an ion channel that plays an important role in the survival of both of these cancers, and extracellular regulated kinases (ERKs),which contributes to the carcinogenesis of many cancers including gastric cancer. As a result, the authors consider the effects of Ginsenoside Rd, NS8593, curcumin, and icariin , known to inhibit TRPM7 and ERK. The authors found that these treatments decrease proliferation and induce apoptosis in studies of gastric and bladder cancer cells.

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