Insulin infusion patches are a common way for diabetics to receive medication. The durability of two different patch adhesives was compared on artificial skin with and without artificial sweat.

In this study, the authors conduct a bibliometric analysis to understand the recent growth in and current state of peripheral nerve regeneration research. They also explored potential future studies.

Cuisine with hot chili peppers can be tasty, but sometimes painful to consume because of the burning sensations caused by the capsaicin molecule. The authors wanted to find the palate reliever that decreases the burning sensation of capsaicin the most by testing water, soft drink, olive oil, milk, and ice-cream as possible candidates. The authors hypothesized that olive oil would be the best palate reliever as it is non-polar like the capsaicin molecule. The authors surveyed 12 panelists with low, medium, and high spice tolerances and found that across all levels of spice tolerance, milk and ice-cream were the best palate relievers and soft drink the worst.

Industrialization has transformed human life and improved it for many. Nonetheless, a side effect has been an increase in chemical waste, which when not disposed of properly, has detrimental effects on surrounding habitats. An increase in ocean acidification could potentially affect many forms of life, disrupting the ecological balance in unforeseeable ways. In this article the authors explore the effect of acidification on corals and shells, and observe that an increase in ocean acidity has a significant effect on corals, but not shells. This illustrates how acidification could negatively affect marine life, and calls our attention to managing the factors that contribute to increasing the pH of the Earth's water bodies.

In this study, the authors use aerosol optical depth data to determine if aerosol levels were lower in major metropolitan areas around the world during the COVID-19 pandemic.

The Scripps National Spelling Bee (SNSB) is an iconic academic competition for United States (US) schoolchildren, held annually since 1925. However, the sizes and geographic distributions of sponsored regions are uneven. One state may send more than twice as many spellers as another state, despite similar numbers in child population. In 2018, the SNSB introduced a wildcard program known as RSVBee, which allowed students to apply to compete as a national finalist, even if they did not win their regional spelling bee. In this study, the authors tested the hypothesis that the geographic distribution of SNSB national finalists more closely matched the child population of the US after RSVBee was implemented.

Tertiary lymphoid structures (TLS) are lymph node-like structures that form at sites of inflammation, and their presence in cancer patients is predictive of a better clinical outcome. One significant obstacle to TLS formation is reduced immune cell infiltration into the tumor microenvironment (TME). Recent studies have shown that vasculature normalizing (VN) agents may override this defect to improve tissue perfusion and increased immune cell entry into the TME. However, their effects on immune cell and tumor cell phenotype remain understudied. Here the authors investigate whether treating tumor cells with VN would reduce their immunosuppressive phenotype and promote production of chemokine that recruit immune cells and foster TLS formation.

Aloe vera and alpha-chymotrypsin have been used in are known for their various wound healing properties. Halder et al hypothesized that these treatments would enhance wound healing in Drosophila melanogaster larvae over 2 weeks by decreasing wound size more effectively compared to controls. The results of two of the treatment groups, Salep and Aloe vera, yielded wound sizes small enough to present a significant percent decrease when compared with the wound sizes of the control group. Their results show support that both Salep and Aloe vera were effective for enhancing wound healing in epithelial cells in D. melanogaster larvae.

One of the greatest challenges we face today is the sustainable production, storage, and distribution of electrical power. One emerging technology with great promise in this area is that of metal-air fuel cells—a long-term and reusable electricity storage system made from a reactive metal anode and a saline solution. In this study the authors tested several different types of metal to determine which was the most suitable for this application. They found that a fuel cell with a magnesium anode was superior to fuel cells made from aluminum or zinc, producing a voltage and current sufficient for real-world applications such as charging a mobile phone.

Ultraviolet (UV) radiation is known to alter DNA structure and impair cellular function in all living organisms. In this study, Lateef et al examine the effects of UV radiation to determine whether antioxidant-enriched nutrition can combat the potential deleterious effects of UV radiation on Drosophila melanogaster. They found that UVB (320nm) radiation caused a 59% decrease in the Drosophila lifespan and mutagenic effects on flies' physical appearance, but did not significantly affect fertility. Curcumin significantly prolonged lifespan and enhanced fertility for both UV- and non-UV-exposed flies. The research demonstrates the positive potential of natural antioxidants as weapons against radiation-induced diseases including cancer.