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Testing Epoxy Strength: The High Strength Claims of Selleys’s Araldite Epoxy Glues

Nguyen et al. | Jul 14, 2020

Testing Epoxy Strength: The High Strength Claims of Selleys’s Araldite Epoxy Glues

Understanding the techniques used to improve the adhesion strength of the epoxy resin is important especially for consumer applications such as repairing car parts, bonding aluminum sheeting, and repairing furniture or applications within the aviation or civil industry. Selleys Araldite epoxy makes specific strength claims emphasizing that the load or weight that can be supported by the adhesive is 72 kg/cm2. Nguyen and Clarke aimed to test the strength claims of Selley’s Araldite Epoxy by gluing two steel adhesion surfaces: a steel tube and bracket. Results showed that there is a lack of consideration by Selleys for adhesion loss mechanisms and environmental factors when accounting for consumer use of the product leading to disputable claims.

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Investigation of Everyday Locations for Antibiotic-Resistant Bacteria in Cambridge, Massachusetts

Maggio et al. | Dec 12, 2019

Investigation of Everyday Locations for Antibiotic-Resistant Bacteria in Cambridge, Massachusetts

In this study, the authors investigate whether antibiotic-resistant bacteria can be found in everyday locations. To do this, they collected samples from multiple high-trafficked areas in Cambridge, MA and grew them in the presence and absence of antibiotics. Interestingly, they grew bacterial colonies from many locations' samples, but not all could grow in the presence of ampicillin. These findings are intriguing and relevant given the rising concern about antibiotic-resistant bacteria.

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The Bioactive Ingredients in Niuli Lactucis Agrestibus Possess Anticancer Effects

Zhu et al. | Sep 17, 2019

The Bioactive Ingredients in Niuli Lactucis Agrestibus Possess Anticancer Effects

In​ the​ field​ of​ medicine,​ natural​ treatments​ are​ becoming ​increasingly ​vital ​towards ​the ​cure ​of ​cancer. Zhu et al. wanted to investigate the effects of lettuce extract on cancer cell survival and proliferation. They used an adenocarcinoma cell line, COLO320DM, to determine whether crude extract from a lettuce species called Niuli​ Lactucis Agrestibus​ would affect cancer cell survival, migration, and proliferation. They found that Niuli extract inhibited cancer cell survival, increased expression of cell cycle inhibitors p21 and p27, and inhibited migration. However, Niuli extract did not have these effects on healthy cells. This work reveals important findings about a potential new source of anti-colorectal cancer compounds.

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The effect of the pandemic on the behavior of junior high school students

Kong Grisius et al. | May 01, 2023

The effect of the pandemic on the behavior of junior high school students
Image credit: Chris Montgomery

Here, seeking to understand how the COVID-19 pandemic affected the social interactions of junior high school students, the authors surveyed students, teachers, and parents. Contrary to their initial hypotheses, the authors found positive correlation between increased virtual contact during social isolation and in-person conflict and disregard for social norms after the pandemic. While the authors identified the limitations of their study, they suggest that further research into the effect of online interactions is becoming increasingly important.

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Homology modeling of clinically-relevant rilpivirine-resistant HIV-RT variants identifies novel rilpivirine analogs with retained binding affinity against NNRTI-resistant HIV mutations

Luk et al. | Jan 24, 2022

Homology modeling of clinically-relevant rilpivirine-resistant HIV-RT variants identifies novel rilpivirine analogs with retained binding affinity against NNRTI-resistant HIV mutations

Human immunodeficiency virus (HIV), which affects tens of millions of individuals worldwide, can lead to acquired immunodeficiency syndrome (AIDS). While there is currently no cure for HIV, the development of small molecule antiretroviral agents has greatly improved the prognosis of infected individuals, especially in developed countries. Here, the authors employ homology modeling and molecular docking towards the identification of novel rilpivirine analogs that retain high binding affinity to clinically relevant rilpivirine-resistant mutations of the HIV reverse transcriptase enzyme.

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Effect of hypervitaminosis A in regenerating planaria: A potential model for teratogenicity testing

Bennet et al. | Dec 12, 2022

Effect of hypervitaminosis A in regenerating planaria: A potential model for teratogenicity testing

This unique research study evaluated the potential use of the flatworm, brown planaria (Dugesia tigrine), as an alternative model for teratogenicity testing. In this study, we exposed amputated planaria to varying concentrations of a known teratogen, vitamin A (retinol), for approximately 2 weeks, and evaluated multiple parameters including the formation of blastema and eyes. The results from this study demonstrated that high concentrations of retinol caused defects in head and eye formation in regenerating planaria, with similarities to vitamin A related teratogenicity findings in mammals. Based on these results, regenerating brown planaria are a promising alternative model for teratogenicity testing, which can potentially be paradigm shifting as it can reduce cost, time, and pregnant animal use in research.

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The Effect of Anubias barteri Plant Species on Limiting Freshwater Acidification

Ramanathan et al. | Jul 06, 2021

The Effect of <i>Anubias barteri</i> Plant Species on Limiting Freshwater Acidification

Research relating to freshwater acidification is minimal, so the impact of aquatic plants, Anubias barteri var. congensis and Anubias barteri var. nana, on minimizing changes in pH was explored in an ecosystem in Northern California. Creek water samples, with and without the aquatic plants, were exposed to dry ice to simulate carbon emissions and the pH was monitored over an eight-hour period. There was a 25% difference in the observed pH based on molar hydrogen ion concentration between the water samples with plants and those without plants, suggesting that aquatic plants have the potential to limit acidification to some extent. These findings can guide future research to explore the viable partial solution of aquatic plants in combating freshwater acidification.

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Androgen Diffusion Patterns in Soil: Potential Watershed Impacts

Corson et al. | Jan 24, 2019

Androgen Diffusion Patterns in Soil: Potential Watershed Impacts

Androgens are natural or synthetic steroid hormones that control secondary male sex characteristics. Androgens are excreted in cattle urine and feces, and can run off or seep into nearby waters, negatively impacting aquatic life and potentially polluting human water sources. Here, the authors investigated the effectiveness of soil as a natural barrier against androgen flow into vulnerable waterways. Their results, obtained by testing diffusion patterns of luminol, an androgen chemical analog, indicated that soil is a poor barrier to androgen diffusion.

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Breast cancer mammographic screening by different guidelines among women of different races/ethnicities

Wang et al. | Aug 27, 2023

Breast cancer mammographic screening by different guidelines among women of different races/ethnicities

Mammographic screening is a common diagnostic tool for breast cancer among average-risk women. The authors hypothesized that adherence rates for mammographic screening may be lower among minorities (non-Hispanic black (NHB) and Hispanic/Latino) than among non-Hispanic whites (NHW) regardless of the guideline applied. The findings support other studies’ results that different racial/ethnic and socio-demographic factors can affect screening adherence. Therefore, healthcare providers should promote breast cancer screening especially among NHW/Hispanic women and women lacking insurance coverage.

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Statistically Analyzing the Effect of Various Factors on the Absorbency of Paper Towels

Tao et al. | Dec 04, 2020

Statistically Analyzing the Effect of Various Factors on the Absorbency of Paper Towels

In this study, the authors investigate just how effectively paper towels can absorb different types of liquid and whether changing the properties of the towel (such as folding it) affects absorbance. Using variables of either different liquid types or the folded state of the paper towels, they used thorough approaches to make some important and very useful conclusions about optimal ways to use paper towels. This has important implications as we as a society continue to use more and more paper towels.

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