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Using explainable artificial intelligence to identify patient-specific breast cancer subtypes

Suresh et al. | Jan 12, 2024

Using explainable artificial intelligence to identify patient-specific breast cancer subtypes

Breast cancer is the most common cancer in women, with approximately 300,000 diagnosed with breast cancer in 2023. It ranks second in cancer-related deaths for women, after lung cancer with nearly 50,000 deaths. Scientists have identified important genetic mutations in genes like BRCA1 and BRCA2 that lead to the development of breast cancer, but previous studies were limited as they focused on specific populations. To overcome limitations, diverse populations and powerful statistical methods like genome-wide association studies and whole-genome sequencing are needed. Explainable artificial intelligence (XAI) can be used in oncology and breast cancer research to overcome these limitations of specificity as it can analyze datasets of diagnosed patients by providing interpretable explanations for identified patterns and predictions. This project aims to achieve technological and medicinal goals by using advanced algorithms to identify breast cancer subtypes for faster diagnoses. Multiple methods were utilized to develop an efficient algorithm. We hypothesized that an XAI approach would be best as it can assign scores to genes, specifically with a 90% success rate. To test that, we ran multiple trials utilizing XAI methods through the identification of class-specific and patient-specific key genes. We found that the study demonstrated a pipeline that combines multiple XAI techniques to identify potential biomarker genes for breast cancer with a 95% success rate.

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Can the attributes of an app predict its rating?

Feng et al. | Jul 03, 2024

Can the attributes of an app predict its rating?
Image credit: Mika Baumeister

In this article the authors looked at different attributes of apps within the Google Play store to determine how those may impact the overall app rating out of five stars. They found that review count, amount of storage needed and when the app was last updated to be the most influential factors on an app's rating.

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The use of computer vision to differentiate valley fever from lung cancer via CT scans of nodules

El Kereamy et al. | Nov 12, 2024

The use of computer vision to differentiate valley fever from lung cancer via CT scans of nodules

Pulmonary diseases like lung cancer and valley fever pose serious health challenges, making accurate and rapid diagnostics essential. This study developed a MATLAB-based software tool that uses computer vision techniques to differentiate between these diseases by analyzing features of lung nodules in CT scans, achieving higher precision than traditional methods.

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Evaluating the performance of Q-learning-based AI in auctions

Liu et al. | Nov 09, 2025

Evaluating the performance of Q-learning-based AI in auctions
Image credit: Liu and Liu

Advertising platforms like Google Ads use AI to drive the algorithms used to maximize advertisers benefits. This study shows that AI does not adjust it strategy based on auction type and highlights the limitations of AI running without explicit guidance.

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Risk assessment modeling for childhood stunting using automated machine learning and demographic analysis

Sirohi et al. | Sep 25, 2022

Risk assessment modeling for childhood stunting using automated machine learning and demographic analysis

Over the last few decades, childhood stunting has persisted as a major global challenge. This study hypothesized that TPTO (Tree-based Pipeline Optimization Tool), an AutoML (automated machine learning) tool, would outperform all pre-existing machine learning models and reveal the positive impact of economic prosperity, strong familial traits, and resource attainability on reducing stunting risk. Feature correlation plots revealed that maternal height, wealth indicators, and parental education were universally important features for determining stunting outcomes approximately two years after birth. These results help inform future research by highlighting how demographic, familial, and socio-economic conditions influence stunting and providing medical professionals with a deployable risk assessment tool for predicting childhood stunting.

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