In this study, the authors investigate the effects that flagella have on E. coli's ability to adhere to glass surfaces.
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Pichia kudriavzevii Yeast Exposure Increases the Asthmatic Behavior of Alveolar Epithelial Cells In Vitro
Asthma affects over 334 million people worldwide and is triggered by inhalation of environmental stimuli. The authors of this study characterized the effect of exposure to common spoilage yeast, Pichia kidriavzevii on alveolar epithelial cells. A direct correlation between infection duration and asthmatic status of these cells was found, indicating the potential for this yeast to be an environmental stimulus of asthma and warranting further study.
Read More...QuitPuff: A Simple Method Using Saliva to Assess the Risk of Oral Pre-Cancerous Lesions and Oral Squamous Cell Carcinoma in Chronic Smokers
Smoking generates free radicals and reactive oxygen species which induce cell damage and lipid peroxidation. This is linked to the development of oral cancer in chronic smokers. The authors of this study developed Quitpuff, simple colorimetric test to measure the extent of lipid peroxidation in saliva samples. This test detected salivary lipid peroxidation with 96% accuracy in test subjects and could serve as an inexpensive, non-invasive test for smokers to measure degree of salivary lipid peroxidation and potential risk of oral cancer.
Read More...Differential MERS-CoV response in different cell types
The authors compare RNA expression profiles across three human cell types following infection with MERS-CoV
Read More...Indole-3 carbinol on lipid accumulation in Caenorhabditis elegans as a novel therapeutic for Type II Diabetes
In this study the authors look at the use of Indole 3 Carbinol as a treatment for Type II Diabetes finding that it may be an effective treatment.
Read More...Effect of heme vs. non-heme iron supplements on gut microbiome fitness
Here, based on identification of iron deficiencies of a majority of people around the world, the authors sought to understand how the two main forms of dietary iron, heme and non-heme, affect the bacteria found in the human gut. by using a cell plate study, they found that bacterial growth increased with increasing concentration os either form of iron, up until the point where the high iron content resulted in cytotoxicity. They suggest this evidence points to the potential dangers of overconsumption of iron.
Read More...Characterizing the evolution of antibiotic resistance in commercial Lactobacillus strains
In this study, the authors studied the ability for bacteria to develop antibiotic resistance over successive generations and modeled the trajectory to predict how antibiotic resistance is developed.
Read More...Analysis of complement system gene expression and outcome across the subtypes of glioma
Here the authors sought to better understand glioma, cancer that occurs in the glial cells of the brain with gene expression profile analysis. They considered the expression of complement system genes across the transcriptional and IDH-mutational subtypes of low-grade glioma and glioblastoma. Based on their results of their differential gene expression analysis, they found that outcomes vary across different glioma subtypes, with evidence suggesting that categorization of the transcriptional subtypes could help inform treatment by providing an expectation for treatment responses.
Read More...How CAFOs affect Escherichia coli contents in surrounding water sources
Commercial Concentrated Animal Feeding Operations (CAFOs) produce large quantities of waste material from the animals being housed in them. These feedlots found across the United States contain livestock that produce waste that results in hazardous runoff. This study examines how CAFOs affect water sources by testing for Escherichia Coli (E. coli) content in bodies of water near CAFOs.
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