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pH-dependent drug interactions with acid reducing agents

Lin et al. | Nov 12, 2024

pH-dependent drug interactions with acid reducing agents
Image credit: The authors

Some cancer treatments lose efficacy when combined with treatments for excessive stomach acid, due to the changes in the stomach environment caused by the stomach acid treatments. Lin and Lin investigate information on oral cancer drugs to see what information is available on interactions of these drugs.

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The correlation between bacteria and colorectal cancer

Zhang et al. | Oct 21, 2024

The correlation between bacteria and colorectal cancer

The authors looked at abundance of bacteria in stool samples from patients with colorectal cancer compared to controls. They found different bacteria that was more prevalent in patients with colorectal cancer as well as bacteria in control patients that may indicate a beneficial gut microbiome.

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Adults’ attitudes toward non-alcoholic beer purchases and consumption by children and adolescents

An et al. | Aug 23, 2024

Adults’ attitudes toward non-alcoholic beer purchases and consumption by children and adolescents
Image credit: The authors

Consumption of non-alcoholic beverages, like non-alcoholic beer, is growing in popularity in the United States. These beverages raise important societal questions, such as whether minors should be allowed to purchase or consume non-alcoholic beer. An and An investigate this issue by surveying adults to see if they support minors purchasing and consuming non-alcoholic beer.

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Diagnosing hypertrophic cardiomyopathy using machine learning models on CMRs and EKGs of the heart

Kolluri et al. | Jul 29, 2024

Diagnosing hypertrophic cardiomyopathy using machine learning models on CMRs and EKGs of the heart
Image credit: Jesse Orrico

Here seeking to develop a method to diagnose, hypertrophic cardiomyopathy which can cause sudden cardiac death, the authors investigated the use of a convolutional neural network (CNN) and long short-term memory (LSTM) models to classify cardiac magnetic resonance and heart electrocardiogram scans. They found that the CNN model had a higher accuracy and precision and better other qualities, suggesting that machine learning models could be valuable tools to assist physicians in the diagnosis of hypertrophic cardiomyopathy.

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Ramifications of natural and artificial sweeteners on the gastrointestinal system

Cowen et al. | Jun 19, 2023

Ramifications of natural and artificial sweeteners on the gastrointestinal system

This study aimed to determine whether artificial sweeteners are harmful to the human microbiome by investigating two different bacteria found to be advantageous to the human gut, Escherichia coli and Bacillus coagulans. Results showed dramatic reduction in bacterial growth for agar plates containing two artificial sweeteners in comparison to two natural sweeteners. This led to the conclusion that both artificial sweeteners inhibit the growth of the two bacteria and warrants further study to determine if zero-sugar sweeteners may be worse for the human gut than natural sugar itself.

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Association between nonpharmacological interventions and dementia: A retrospective cohort study

Yerabandi et al. | Jan 09, 2023

Association between nonpharmacological interventions and dementia: A retrospective cohort study
Image credit: Ross Sneddon

Here, the authors investigated the role of nonpharmacological interventions in preventing or delaying cognitive impairment in individuals with and without dementia. By using a retrospective case-control study of 22 participants across two senior centers in San Diego, they found no significant differences in self-reported activities. However, they found that their results reflected activity rather than the activity itself, suggesting the need for an alternative type of study.

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