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Culturally Adapted Assessment Tool for Autism Spectrum Disorder and its Clinical Significance

Das et al. | Apr 19, 2021

Culturally Adapted Assessment Tool for Autism Spectrum Disorder and its Clinical Significance

Diagnosing of Autism Spectrum Disorder (ASD) using tools developed in the West is challenging in the Indian setting due to a huge diversity in sociocultural and economic backgrounds. Here, the authors developed a home-based, audiovisual game app (Autest) suitable for ASD risk assessment in Indian children under 10 years of age. Ratings suggested that the tool is effective and can reduce social inhibition and facilitate assessment. Further usage and development of Autest can improve risk assessment and early intervention measures for children with ASD in India.

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Development and Implementation of Enzymatic and Volatile Compound-based Approaches for Instantaneous Detection of Pathogenic Staphylococcus aureus

Nori et al. | Feb 20, 2021

Development and Implementation of Enzymatic and Volatile Compound-based Approaches for Instantaneous Detection of Pathogenic <i>Staphylococcus aureus</i>

Staphylococcus aureus (S. aureus) has a mortality rate of up to 30% in developing countries. The purpose of this experiment was to determine if enzymatic and volatile compound-based approaches would perform more quickly in comparison to existing S. aureus diagnostic methods and to evaluate these novel methods on accuracy. Ultimately, this device provided results in less than 30 seconds, which is much quicker than existing methods that take anywhere from 10 minutes to 48 hours based on approach. Statistical analysis of accuracy provides preliminary confirmation that the device based on enzymatic and volatile compound-based approaches can be an accurate and time-efficient tool to detect pathogenic S. aureus.

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Effect Of SMC On The Growth Of Bean, Cherry Tomato And Roma Tomato Plant

Rao et al. | Sep 12, 2020

Effect Of SMC On The Growth Of Bean, Cherry Tomato And Roma Tomato Plant

Mushroom compost, also called Spent Mushroom Substrate or Spent Mushroom Compost (SMC), is suitable for a variety of plants. Previous research has found that the application of SMC will increase plant growth. However, it is unclear which exact proportions of SMC and soil will maximize tomato and bean plant growth. We showed that the hypothesized growth media with 30% SMC optimizes seed germination, plant height, number of leaves, and survival rate compared to other combinations of growth media. Our research suggests that SMC is a useful alternative for conventional fertilizers.

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Combating drug resistance in cancer cells: Cooperative effect of green tea and turmeric with chemotherapeutic drug

Nair et al. | Jul 27, 2020

Combating drug resistance in cancer cells: Cooperative effect of green tea and turmeric with chemotherapeutic drug

The major drawback of chemotherapy regimens for treating cancer is that the cancerous cells acquire drug resistance and become impervious to further dose escalation. Keeping in mind the studied success of herbal formulations with regard to alternative treatments for cancer, we hypothesized that the use of a chemotherapeutic drug and proprietary herbal formulation, HF1, would combat this phenomenon when administered with common chemotherapeutic drug 5FU. Results demonstrated a cooperative effect between HF1 and 5FU on the drug resistant cell line, implying that administration of HF1 with 5FU results in cell death as measured by MTT assay.

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Spider Density Shows Weak Relationship with Vegetation Density

Ryon et al. | Jul 03, 2020

Spider Density Shows Weak Relationship with Vegetation Density

Evidence supports that spiders have many ecological benefits including insect control and predation in the food chain. In this study the authors investigate that whether the percent of vegetation coverage and spider density are correlated. They determine that despite the trend there is no statistically significant correlation.

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Characterizing Quorum Sensing-Induced Bioluminescence in Variable Volumes With Vibrio fischeri Using Computer Processing Methods

Abdel-Azim et al. | Jun 22, 2020

Characterizing Quorum Sensing-Induced Bioluminescence in Variable Volumes With <em>Vibrio fischeri</em> Using Computer Processing Methods

Understanding how bacteria respond to other bacteria could facilitate their ability to initiate and maintain their infectiousness. The phenomenon by which bacteria signal to each other via chemical signals is called quorum sensing, which could be targeted to deter bacterial infection in some cases if better understood. In this article, the authors study how a bacterium called V. fischeri uses quorum sensing to change bioluminescence, an easy readout that facilitates studying quorum sensing in this strain.

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The Effect of Different Fructose Diets on the Lifespan of C. elegans

Chen et al. | May 10, 2020

The Effect of Different Fructose Diets on the Lifespan of <em>C. elegans</em>

High-fructose diets consumed widely in modern societies predisposes to metabolic diseases such as diabetes. Using the worm C. elegans, the authors of this study investigated the effect of fructose on the worm's survival rates. They found that worms fed 15% fructose had a lower life expectancy than those on a fructose-free diet. These results suggest that, like in humans, fructose has a negative effect on worm survival, which makes them an easy, attractive model to study the effects of fructose on health.

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