The authors looked at the relation between stress and motivation in high school students with 4+ AP classes that also played a varsity sport. No distinct correlation was observed, however, results indicated that there are other factors at play that influence both stress and motivation.
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Exercise, grades, stress, and learning experiences during remote learning due to the COVID-19 pandemic
In this study, the authors survey middle and high school students in different states in the U.S. to evaluate stress levels, learning experiences, and activity levels during the COVID-19 pandemic.
Read More...Evaluation of Tea Extract as an Inhibitor of Oxidative Stress in Prostate Cells
One important factor that contributes to human cancers is accumulated damage to cells' DNA due to the oxidative stress caused by free radicals. In this study, the authors investigate the effects of several different tea leaf extracts on oxidative stress in cultured human prostate cells to see if antioxidants in the tea leaves could help protect cells from this type of DNA damage. They found that all four types of tea extract (as well as direct application of the antioxidant EGCG) improved the outcomes for the cultured cells, with white tea extract having the strongest effect. This research suggests that tea extracts and the antioxidants that they contain may have applications in the treatment of the many diseases associated with cellular DNA damage, including cancer.
Read More...Formulation of novel polyherbal compound MAT20 with phytochemicals found in amla, tulsi, and moringa
With herbal plants providing an address to the adverse effects of oxidative stress found within the body, the authors of this article develop and assess a novel compound (“MAT20”) that blends three herbal plants for optimal oxidative stress relief.
Read More...Namaste to Wellbeing? The Effect of Yoga on the Health of African American High School Students
The authors examined the potential psychological and physiological benefits of yoga for African American high school students who attended a rigorous college preparatory program - they found that the perceived stress levels of yoga participants decreased 13% compared to the control group, though no significant changes in physiology were noted.
Read More...The Protective Effects of Panax notoginseng Saponin on the Blood-Brain Barrier via the Nrf2/ARE Pathway in bEnd3 Cells
Disruption of the blood-brain barrier (BBB) is related to many neurological disorders, and can be caused by oxidative stress to cerebral microvascular endothelial cells (CMECs) composing the BBB. The authors of the paper investigated the protective effects of the total saponins in the leaves of Panax notoginseng (LPNS) on oxidative-stress-induced damage in a mouse cerebral microvascular endothelial cell line.
Read More...Expressional correlations between SERPINA6 and pancreatic ductal adenocarcinoma-linked genes
Pancreatic ductal adenocarcinoma (PDAC) is the most common form of pancreatic cancer, with early diagnosis and treatment challenges. When any of the genes KRAS, SMAD4, TP53, and BRCA2 are heavily mutated, they correlate with PDAC progression. Cellular stress, partly regulated by the gene SERPINA6, also correlates with PDAC progression. When SERPINA6 is highly expressed, corticosteroid-binding globulin inhibits the effect of the stress hormone cortisol. In this study, the authors explored whether there is an inverse correlation between the expression of SERPINA6 and PDAC-linked genes.
Read More...Potential Multifunctional Agents for Dual Therapy of Age-Related and Associated Diseases: Alzheimer’s Disease and Type 2 Diabetes Mellitus
Studies show an age-related link between Alzheimer’s Disease and Type 2 Diabetes Mellitus with oxidative stress a characteristic of both. Here, methanolic fractionations and extracts of four Ayurvedic plants were assessed for their protective abilities using a number of in vitro assays. Extracts inhibited oxidative stress and reduced activity of key enzymes involved in the pathogenesis of both diseases in neuroblastoma cells.
Read More...Upregulation of the Ribosomal Pathway as a Potential Blood-Based Genetic Biomarker for Comorbid Major Depressive Disorder (MDD) and PTSD
Major Depressive Disorder (MDD), and Post-Traumatic Stress Disorder (PTSD) are two of the fastest growing comorbid diseases in the world. Using publicly available datasets from the National Institute for Biotechnology Information (NCBI), Ravi and Lee conducted a differential gene expression analysis using 184 blood samples from either control individuals or individuals with comorbid MDD and PTSD. As a result, the authors identified 253 highly differentially-expressed genes, with enrichment for proteins in the gene ontology group 'Ribosomal Pathway'. These genes may be used as blood-based biomarkers for susceptibility to MDD or PTSD, and to tailor treatments within a personalized medicine regime.
Read More...Estimating the Young’s Modulus of spaghetti with a buckling experiment
The Young's Modulus of a structural material is a measure of its elasticity and is defined as the ratio of the tensile stress to tensile strain. This study aims to investigate the Young's Modulus of pasta with different diameters.
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