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A novel approach for early detection of Alzheimer’s disease using deep neural networks with magnetic resonance imaging

Ganesh et al. | Mar 20, 2022

A novel approach for early detection of Alzheimer’s disease using deep neural networks with magnetic resonance imaging

In the battle against Alzheimer's disease, early detection is critical to mitigating symptoms in patients. Here, the authors use a collection of MRI scans, layering with deep learning computer modeling, to investigate early stages of AD which can be hard to catch by human eye. Their model is successful, able to outperform previous models, and detected regions of interest in the brain for further consideration.

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The Effect of Anubias barteri Plant Species on Limiting Freshwater Acidification

Ramanathan et al. | Jul 06, 2021

The Effect of <i>Anubias barteri</i> Plant Species on Limiting Freshwater Acidification

Research relating to freshwater acidification is minimal, so the impact of aquatic plants, Anubias barteri var. congensis and Anubias barteri var. nana, on minimizing changes in pH was explored in an ecosystem in Northern California. Creek water samples, with and without the aquatic plants, were exposed to dry ice to simulate carbon emissions and the pH was monitored over an eight-hour period. There was a 25% difference in the observed pH based on molar hydrogen ion concentration between the water samples with plants and those without plants, suggesting that aquatic plants have the potential to limit acidification to some extent. These findings can guide future research to explore the viable partial solution of aquatic plants in combating freshwater acidification.

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Identification of microwave-related changes in tissue using an ultrasound scan

Shariff et al. | Apr 24, 2024

Identification of microwave-related changes in tissue using an ultrasound scan
Image credit: Shariff and Shariff 2024

Microwave energy (ME) is used in the medical field to denature protein structures, resulting in inactivation or destruction of abnormal cells. Identifying the extent of destruction of abnormal tissue (cancer tissue or tissue with abnormal electrical activity) is essential for accomplishing successful therapy and reducing collateral damage. Our study was an ex vivo assessment of the changes on ultrasound scans (US) in chicken tissue exposed to ME. We hypothesized that any changes in tissue structures would be recognized on the reflected ultrasound waves. Ultrasound scans of tissues change with exposure to microwaves with increasing reflection of ultrasound waves. With exposure to microwaves, surface level brightness on the ultrasound scans increases statistically significantly. The findings could be used in heat related (ME and radiofrequency) procedures where clinicians would be able to actively assess lesions in real-time. Further studies are required to assess changes in tissue during active exposure to different types of energies.

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Phages Can Be More Effective and Specific Than Antibiotics in Combating Bacteria

Wu et al. | Feb 17, 2019

Phages Can Be More Effective and Specific Than Antibiotics in Combating Bacteria

Phage therapy has been suggested as an alternative to antibiotics because bacteria resistant to antibiotics may still be susceptible to phages. However, phages may have limited effectiveness in combating bacteria since bacteria possess several antiviral defense mechanisms and can quickly develop resistance to phages. In this study, Wu and Pinta compare the effectiveness and specificity of antibiotics and phages in combating bacteria. They found that T4 phages are more specific and effective in fighting or inhibiting both antibiotic-resistant and sensitive bacteria than antibiotics, suggesting that phage therapy can be developed as an efficient tool to combat antibiotic-resistant bacteria.

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COVID 19 and the perceived impacts on adolescents’ and young adults’ mental health: A quantitative survey

Kumar et al. | Jul 31, 2023

COVID 19 and the perceived impacts on adolescents’ and young adults’ mental health: A quantitative survey
Image credit: Nick Fewings

Here, recognizing the effects of the COVID-19 pandemic on young peoples' mental health and wellbeing the authors used an online survey which included the short General Health Questionnaire (GHQ-12) to probe 102 young adults. Overall they found that young adults perceived the pandemic to be detrimental to many areas of their wellbeing, with females and those aged 18-19 and 22-23 reporting to be the most significantly impacted.

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The Effects of Ezetimibe on Triglyceride and Alanine Transaminase Reduction in Drosophila Melanogaster Model of Nonalcoholic Fatty Liver Disease (NAFLD)

Dania et al. | Apr 30, 2020

The Effects of Ezetimibe on Triglyceride and Alanine Transaminase Reduction in <i>Drosophila Melanogaster</i> Model of Nonalcoholic Fatty Liver Disease (NAFLD)

Nonalcoholic Fatty Liver Disease (NAFLD) is a condition where a surplus of triglycerides or fat are present in the liver. In this study, ezetimibe, a cholesterol lowering drug, was used to treat flies modeling NAFLD. Compared to the coconut oil fed flies that were transferred to the control medium, the flies transferred to the control medium treated with ezetimibe showed a decrease in their triglyceride and alanine transaminase level.

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Bacteroides thetaiotaomicron Growth Numbers Are Unchanged in the Presence of Yogurt

Phan et al. | Dec 29, 2016

<i>Bacteroides thetaiotaomicron</i> Growth Numbers Are Unchanged in the Presence of Yogurt

Disruptions to the microbiome, specifically the imbalance in the two major phyla, the Firmicutes and the Bacteroidetes, have been linked to the development of obesity. This study explored whether or not Fage plain total 0% Greek yogurt, which contains live and active bacterial cultures belonging to the Firmicute phylum, could decrease the numbers of Bacteroides thetaiotaomicron, an organism found in the human gut that belongs to the Bacteroidetes phylum.

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The Effects of Ultraviolet Light on Escherichia coli

Kodoth et al. | Sep 07, 2015

The Effects of Ultraviolet Light on <em>Escherichia coli</em>

In this study E. coli bacteria was exposed to small UV lights currently used in school laboratories to see the effect on colony growth. This project explores how UV radiation methods could be applied in common households to inhibit bacterial growth.

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