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Cathodal Galvanotaxis: The Effect of Voltage on the distribution of Tetrahymena pyriformis

Zheng et al. | Jun 10, 2019

Cathodal Galvanotaxis: The Effect of Voltage on the distribution of <em>Tetrahymena pyriformis</em>

The surface of the unicellular eukaryote, Tetrahymena pyriformis, is covered with thousands of hair-like cilia. These cilia are very similar to cilia of the human olfactory and respiratory tracts making them model organisms for studying cilia function and pathology. The authors of this study investigated the effect of voltage on T. pyriformis galvanotaxis, the movement towards an electrical stimulus. They observed galvanotaxis towards the cathode at voltages over 4V which plateau, indicating opening of voltage gated-ion channels to trigger movement.

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The effect of the pandemic on the behavior of junior high school students

Kong Grisius et al. | May 01, 2023

The effect of the pandemic on the behavior of junior high school students
Image credit: Chris Montgomery

Here, seeking to understand how the COVID-19 pandemic affected the social interactions of junior high school students, the authors surveyed students, teachers, and parents. Contrary to their initial hypotheses, the authors found positive correlation between increased virtual contact during social isolation and in-person conflict and disregard for social norms after the pandemic. While the authors identified the limitations of their study, they suggest that further research into the effect of online interactions is becoming increasingly important.

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Refinement of Single Nucleotide Polymorphisms of Atopic Dermatitis related Filaggrin through R packages

Naravane et al. | Oct 12, 2022

Refinement of Single Nucleotide Polymorphisms of Atopic Dermatitis related Filaggrin through R packages

In the United States, there are currently 17.8 million affected by atopic dermatitis (AD), commonly known as eczema. It is characterized by itching and skin inflammation. AD patients are at higher risk for infections, depression, cancer, and suicide. Genetics, environment, and stress are some of the causes of the disease. With the rise of personalized medicine and the acceptance of gene-editing technologies, AD-related variations need to be identified for treatment. Genome-wide association studies (GWAS) have associated the Filaggrin (FLG) gene with AD but have not identified specific problematic single nucleotide polymorphisms (SNPs). This research aimed to refine known SNPs of FLG for gene editing technologies to establish a causal link between specific SNPs and the diseases and to target the polymorphisms. The research utilized R and its Bioconductor packages to refine data from the National Center for Biotechnology Information's (NCBI's) Variation Viewer. The algorithm filtered the dataset by coding regions and conserved domains. The algorithm also removed synonymous variations and treated non-synonymous, frameshift, and nonsense separately. The non-synonymous variations were refined and ordered by the BLOSUM62 substitution matrix. Overall, the analysis removed 96.65% of data, which was redundant or not the focus of the research and ordered the remaining relevant data by impact. The code for the project can also be repurposed as a tool for other diseases. The research can help solve GWAS's imprecise identification challenge. This research is the first step in providing the refined databases required for gene-editing treatment.

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The effect of neuroinflammation and oxidative stress on the recovery time of seizures

Kantipudi et al. | Jul 31, 2023

The effect of neuroinflammation and oxidative stress on the recovery time of seizures

Neuroinflammation and oxidative stress are both known to play a role in the occurrence and severity of seizures. This study tested effects of oxidative stress from seizures by evaluating the longevity, egg-laying, and electroshock resilience of C. elegans. Results revealed that oxidative stress and neuroinflammation diminish longevity and reproductivity while also increasing recovery time after seizures in C. elegans. This research can help lead to future studies and may also lead to finding new therapeutics for epilepsy.

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Effect Of SMC On The Growth Of Bean, Cherry Tomato And Roma Tomato Plant

Rao et al. | Sep 12, 2020

Effect Of SMC On The Growth Of Bean, Cherry Tomato And Roma Tomato Plant

Mushroom compost, also called Spent Mushroom Substrate or Spent Mushroom Compost (SMC), is suitable for a variety of plants. Previous research has found that the application of SMC will increase plant growth. However, it is unclear which exact proportions of SMC and soil will maximize tomato and bean plant growth. We showed that the hypothesized growth media with 30% SMC optimizes seed germination, plant height, number of leaves, and survival rate compared to other combinations of growth media. Our research suggests that SMC is a useful alternative for conventional fertilizers.

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Mapping the Electromagnetic Field in Front of a Microwave Oven

Xiang et al. | Sep 21, 2019

Mapping the Electromagnetic Field in Front of a Microwave Oven

There is limited evidence that extended exposure to an electromagnetic field (EMF) has negative health effects on humans. The authors measured the power density and strength of EMF at different distances and directions in front of a microwave oven, and they discuss the safety of different distances.

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Estimation of Reproduction Number of Influenza in Greece using SIR Model

Skarpeti et al. | Nov 18, 2020

Estimation of Reproduction Number of Influenza in Greece using SIR Model

In this study, we developed an algorithm to estimate the contact rate and the average infectious period of influenza using a Susceptible, Infected, and Recovered (SIR) epidemic model. The parameters in this model were estimated using data on infected Greek individuals collected from the National Public Health Organization. Our model labeled influenza as an epidemic with a basic reproduction value greater than one.

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The study of technology and the use of individual cognitive effort

Neravetla et al. | Jan 24, 2023

The study of technology and the use of individual cognitive effort
Image credit: Glenn Carstens-Peters

A trial study was performed in 2021 to investigate the link between technology and transactive memory. Transactive memory is shared knowledge in which members share the responsibility to encode, store, and retrieve certain tasks or assignments, leading to a successful and collective performance. We hypothesize that a participants’ expected access to an external source affects the recall rate and retrieval of information.

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