![Studying habitability of the exoplanents Kepler-504 b, Kepler-315 b, and Kepler-315 c](/rails/active_storage/representations/proxy/eyJfcmFpbHMiOnsibWVzc2FnZSI6IkJBaHBBazRNIiwiZXhwIjpudWxsLCJwdXIiOiJibG9iX2lkIn19--a84491ae7aa62d26baf8144836a2f4c0321c2d73/eyJfcmFpbHMiOnsibWVzc2FnZSI6IkJBaDdCem9MWm05eWJXRjBTU0lJYW5CbkJqb0dSVlE2QzNKbGMybDZaVWtpRFRZd01IZzJNREErQmpzR1ZBPT0iLCJleHAiOm51bGwsInB1ciI6InZhcmlhdGlvbiJ9fQ==--a3b53ba1a0f83efef18f6e75a8d4ce784384bee2/JEI-22-033.jpg)
The authors explore how similar exoplanets are to Earth and whether they could be inhabited by humans and other living organisms.
Read More...Studying habitability of the exoplanents Kepler-504 b, Kepler-315 b, and Kepler-315 c
The authors explore how similar exoplanets are to Earth and whether they could be inhabited by humans and other living organisms.
Read More...Contrasting role of ASCC3 and ALKBH3 in determining genomic alterations in Glioblastoma Multiforme
Glioblastoma Multiforme (GBM) is the most malignant brain tumor with the highest fraction of genome alterations (FGA), manifesting poor disease-free status (DFS) and overall survival (OS). We explored The Cancer Genome Atlas (TCGA) and cBioportal public dataset- Firehose legacy GBM to study DNA repair genes Activating Signal Cointegrator 1 Complex Subunit 3 (ASCC3) and Alpha-Ketoglutarate-Dependent Dioxygenase AlkB Homolog 3 (ALKBH3). To test our hypothesis that these genes have correlations with FGA and can better determine prognosis and survival, we sorted the dataset to arrive at 254 patients. Analyzing using RStudio, both ASCC3 and ALKBH3 demonstrated hypomethylation in 82.3% and 61.8% of patients, respectively. Interestingly, low mRNA expression was observed in both these genes. We further conducted correlation tests between both methylation and mRNA expression of these genes with FGA. ASCC3 was found to be negatively correlated, while ALKBH3 was found to be positively correlated, potentially indicating contrasting dysregulation of these two genes. Prognostic analysis showed the following: ASCC3 hypomethylation is significant with DFS and high ASCC3 mRNA expression to be significant with OS, demonstrating ASCC3’s potential as disease prediction marker.
Read More...Measuring Exoplanetary Radii Using Transit Photometry
Studying exoplanets, or planets that orbit a star other than the Sun, is critical to a greater understanding the formation of planets and how Earth's solar system differs from others. In this study the authors analyze the transit light curves of three hot Jupiter exoplanets to ultimately determine if and how these planets have changed since their discovery.
Read More...A Phylogenetic Study of Conifers Describes Their Evolutionary Relationships and Reveals Potential Explanations for Current Distribution Patterns
Many species of trees are distributed widely around the world, though not always in a way that makes immediate sense. The authors here use genetic information to help explain the geographic distribution of various conifer species throughout the world.
Read More...EEG study of virtual learning demonstrates worsened learning outcomes and increased mirror neuron activation
In this article, Choi and Rossitto investigated the limitations of virtual learning by examining in-person dance learning compared to virtual dance learning while wearing EEG headsets. They found that in-person learners outperformed virtual learners and that virtual learners had higher mirror neuron activity as assessed by Mu rhythm power.
Read More...Testing the Effects of Resveratrol, Apigenin, and Glucosamine to Effectively Reduce Prostate Cancer Cell Proliferation, Migration Levels, and Increase Apoptosis
The current five-year survival rate of metastasized prostate cancer is only 30% and occurs in every one in nine men. Researchers have shown that people with a type of dwarfism called Laron’s Syndrome are immune to cancer due to their low levels of insulin-like growth factor-1 (IGF-1). For this reason, experimentally modifying the level of IGF-1 could provide better insight into whether lowering the levels of IGF-1 in prostate cancer cell lines (e.g. PC-3) could be an effective treatment to reduce their rates of proliferation and migration and increase apoptosis. We selected three compounds, which researchers have shown decrease IGF-1 levels, to test and combine to determine which is the most promising.
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