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The misfolding of proteins leads to numerous diseases including Akzheimer’s, Parkinson’s and Type II Diabetes. Understanding of exactly how proteins fold is crucial for many medical advancements. Chenna and Englander addressed this problem by measuring the rate of hydrogen-deuterium exchange within proteins exposed to deuterium oxide in order to further elucidate the process of protein folding. Here, mass spectrometry was used to measure exchange in Cytochrome c and was compared to archived 1H NMR data.

Stem cells are at the forefront of research in regenerative medicine and cell therapy. Two essential properties of stem cells are self-renewal and potency, having the ability to specialize into different types of cells. Here, Park and Jeong took advantage of previously identified stem cell transcription factors associated with potency to differentiate umbilical cord mesenchymal stem cells (US-MSCs) from morphologically similar fibroblasts. Western blot analysis of the transcription factors Klf4, Nanog, and Sox2 revealed their expression was unique to US-MSCs providing insight for future methods of differentiating between these cell lines.

Patel et al. explore whether T. paniculatum plant extract can work with modern antibiotics to increase antibiotic efficacy against common disease-causing bacteria. The plant extract in conjunction with the antibiotic shows promise in battling S. aureus. The authors present a cost-effective method to increase antibiotic efficacy in a time where antibiotic resistant bacteria is becoming a growing problem.

In this study, preparations of ginger were tested for an effect on the growth of four common bacterial species.

Here the authors investigated the use of an affordable gas sensor to detect volatile organic compound (VOC) emissions as an early indicator of tree disease, finding statistically significant differences in VOCs between diseased and non-diseased ash, beech, and maple trees. They suggest this sensor has potential for widespread early disease detection, but call for further research with larger sample sizes and diverse locations.

It can be challenging for the general public to understand data on medical risk. Weseley-Jones and Mordechai tackle this issue by conducting a survey to assess people's skill and comfort with understanding medical risk information in percentage and frequency formats.

Plant diseases can cause up to 50% crop yield loss for the popular tomato plant. A mobile device-based method to identify diseases from photos of symptomatic leaves via computer vision can be more effective due to its convenience and accessibility. To enable a practical mobile solution, a “shallow” convolutional neural networks (CNNs) with few layers, and thus low computational requirement but with high accuracy similar to the deep CNNs is needed. In this work, we explored if such a model was possible.

The authors looked at how the presence of difference antibiotic resistance genes would influence antibiotic resistance in Staphylococcus aureus.

The authors looked at the ability of berberine in combination with melatonin to have anticancer effects when tested in an in vitro cell model.

The authors looked at genes that were differentially expressed in patients who had and had not had febrile seizures to determine what differences in gene expression existed.