The density of stomata, or stomatal index, in plant leaves is correlated with the plant's rate of photosynthesis, and affected by the plant's climate. In this paper, authors measure the stomatal index of five plant species to derive their rates of photosynthesis. These results could help track changes in plants' photosynthetic rates with changing climate.
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Survival analysis in cardiovascular epidemiology: nexus between heart disease and mortality
In 2021, over 20 million people died from cardiovascular diseases, highlighting the need for a deeper understanding of factors influencing heart failure outcomes. This study examined multiple variables affecting mortality after heart failure, using random forest models to identify time, serum creatinine, and ejection fraction as key predictors. These findings could contribute to personalized medicine, improving survival rates by tailoring treatment strategies for heart failure patients.
Read More...Osmotic characteristics of water retention structures of Bursera microphylla in relation to soil salinity
This study hypothesized that sodium chloride was taken up through plant root structures to facilitate water transportation, and that sodium chloride accumulation was directly proportional to the soil salinity. Results showed that most cells within the “bulb” structures were isotonic at a concentration approximately twice as high as that of root tissue and ambient soil salinity, therefore supporting the presented hypothesis.
Read More...Cytotoxicity evaluation of Amaranthus extracts compared with AS20 on MCF-7 cancer cells
The authors test the antiproliferative and apoptosis-inducing properties of an extract created from a traditional Indian medicinal plant of the Amaranthus genus.
Read More...Can the nucleotide content of a DNA sequence predict the sequence accessibility?
Sequence accessibility is an important factor affecting gene expression. Sequence accessibility or openness impacts the likelihood that a gene is transcribed and translated into a protein and performs functions and manifests traits. There are many potential factors that affect the accessibility of a gene. In this study, our hypothesis was that the content of nucleotides in a genetic sequence predicts its accessibility. Using a machine learning linear regression model, we studied the relationship between nucleotide content and accessibility.
Read More...Gene expression profiling of MERS-CoV-London strain
In this study, the authors identify transcripts and gene networks that are changed after infection with the Middle East Respiratory Syndrome-related coronavirus (MERS-CoV).
Read More...Reducing PMA-induced COX-2 expression using a herbal formulation in MCF-7 breast cancer cells
In this study, the authors investigate the effect of a herbal formulation on Cyclooxygenase-2 (COX-2) expression in cancer cells. High levels of COX-2 correlates with worsened cancer outcomes and the authors hypothesize that the formulation will inhibit COX-2 levels.
Read More...In vitro Comparison of Anticancer and Immunomodulatory Activities of Resveratrol and its Oligomers
Resveratrol is a type of stillbenoid, a phenolic compound produced in plants, that is known for its anti-inflammatory and anticancer effects. Many oligomers of resveratrol have recently been isolated their bioactivities remain unknown. Here, authors compared the bioactivities of resveratrol with natural dimers (ε-viniferin and gnetin H) and trimers (suffruticosol B and C). Results provide preliminary evidence that resveratrol oligomers could be potential preventive or therapeutic agents for cancers and other immune-related diseases
Read More...Herbal Extracts Alter Amyloid Beta Levels in SH-SY5Y Neuroblastoma Cells
Alzheimer’s disease (AD) is a type of dementia that affects more than 5.5 million Americans, and there are no approved treatments that can delay the advancement of the disease. In this work, Xu and Mitchell test the effects of various herbal extracts (bugleweed, hops, sassafras, and white camphor) on Aβ1-40 peptide levels in human neuroblastoma cells. Their results suggest that bugleweed may have the potential to reduce Aβ1-40 levels through its anti-inflammatory properties.
Read More...The Effects of L-glutamate, L-glutamine, and L-aspartic Acid on the Amylase Production of E. coli Transformed With pAmylase
Human amylase is important to digestion and has broad applications for therapeutic use in patients with pancreatic insufficiency. The authors present a method to increase amylase production in E. coli by adding the amino acids L-glutamate and L-glutamine.
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