With molecular energy being an integral element to the study of molecules and molecular interactions, computational methods to determine molecular energy are used for the preservation of time and resources. However, these computational methods have high demand for computer resources, limiting their widespread feasibility. The authors of this study employed machine learning to address this disadvantage, utilizing neural networks trained on different representations of molecules to predict molecular properties without the requirement of computationally-intensive processing. In their findings, the authors determined the Feedforward Neural Network, trained by two separate models, as capable of predicting molecular energy with limited prediction error.
Read More...Browse Articles
How Ethanol Concentration Affects Catalase Catalysis of Hydrogen Peroxide
Catalase is a critical enzyme in the human body because it is capable of converting potentially dangerous hydrogen peroxide into water and oxygen. This work asks whether ethanol affects catalase activity, as alcohol consumption has been often linked to hepatitis occurring in the liver, where catalase level is especially high, and ethanol is known to be capable of denaturing proteins. Testing different concentrations of ethanol found that higher concentrations reduced the activity of catalase. This work has important implications on the negative effects of ethanol on metabolism, in which catalase plays an important role, and protein function more broadly.
Read More...Reducing PMA-induced COX-2 expression using a herbal formulation in MCF-7 breast cancer cells
In this study, the authors investigate the effect of a herbal formulation on Cyclooxygenase-2 (COX-2) expression in cancer cells. High levels of COX-2 correlates with worsened cancer outcomes and the authors hypothesize that the formulation will inhibit COX-2 levels.
Read More...Determination of Optimal Relevant Joint Angles for Vertical Jump Height Across Teenagers with Differing Amounts of Jumping Experience
Reaching one’s maximum jump height requires optimizing one’s jump techniques. In order to find this optimal jump technique, three high school participants with varying vertical jump (VJ) abilities recorded videos of themselves with varying degrees of maximum/minimum shoulder, knee, and hip angles—with or without respect to the horizontal—at the isometric phase of a regular countermovement (CM) VJ or countermovement jump (CMJ). Results showed that the shoulder angle without respect to the horizontal (SA), knee angle with respect to the horizontal (KAH), and the hip angle with respect to the horizontal (HAH) possessed a more consistent correlation with VJ height across the subjects compared to the same respective angles with opposite relations to the horizontal.
Read More...Leveraging E-Waste to Enhance Water Condensation by Effective Use of Solid-state Thermoelectric Cooling
Water scarcity affects upwards of a billion people worldwide today. This project leverages the potential of capturing humidity to build a high-efficiency water condensation device that can generate water and be used for personal and commercial purposes. This compact environment-friendly device would have low power requirements, which would potentially allow it to utilize renewable energy sources and collect water at the most needed location.
Read More...Analysis of the Exoplanet HD 189733b to Confirm its Existence
In this study, the authors study features of exoplanet 189733 b. This exoplanet, or planets that orbit stars other than the Sun, is found in the HD star system. Using a DSLR camera, they constructed a high caliber exoplanet transit detection tracker to study the orbital periods, radial velocity, and photometry of 189733 b. They then compared results from their system to data collected by other high precision studies. What they found was that their system produced results supporting previously published studies. These results are exciting results from the solar system demonstrating the importance of validating radial velocity and photometry data using high-precision studies.
Read More...Investigation of Everyday Locations for Antibiotic-Resistant Bacteria in Cambridge, Massachusetts
In this study, the authors investigate whether antibiotic-resistant bacteria can be found in everyday locations. To do this, they collected samples from multiple high-trafficked areas in Cambridge, MA and grew them in the presence and absence of antibiotics. Interestingly, they grew bacterial colonies from many locations' samples, but not all could grow in the presence of ampicillin. These findings are intriguing and relevant given the rising concern about antibiotic-resistant bacteria.
Read More...An Analysis of Soil Microhabitats in Revolutionary War, Civil War, and Modern Graveyards on Long Island, NY
Previously established data indicate that cemeteries have contributed to groundwater and soil pollution, as embalming fluids can impact the microbiomes that exist in decomposing remains. In this study, Caputo et al hypothesized that microbial variation would be high between cemeteries from different eras due to dissimilarities between embalming techniques employed, and furthermore, that specific microbes would act as an indication for certain contaminants. Overall, they found that there is a variation in the microbiomes of the different eras’ cemeteries according to the concentrations of the phyla and their more specific taxa.
Read More...Functional Network Connectivity: Possible Biomarker for Autism Spectrum Disorders (ASD)
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder and is difficult to diagnose in young children. Here magnetoencephalography was used to compare the brain activity in patients with ASD to patients in a control group. The results show that patients with ASD have a high level of activity in different areas of the brain than those in the control group.
Read More...The Dependence of CO2 Removal Efficiency on its Injection Speed into Water
Recent research confirms that climate change, driven by CO2 emissions from burning fossil fuels, poses a significant threat to humanity. In response, authors explore methods to remove CO2 from the atmosphere, including breaking its molecular bonds through high-speed collisions.
Read More...