In this study, the impact of fluorination of heterocyclic drug Allopurinol on its stability and other chemical properties is investigated.
Read More...A computational quantum chemical study of fluorinated Allopurinol
In this study, the impact of fluorination of heterocyclic drug Allopurinol on its stability and other chemical properties is investigated.
Read More...Leveraging transfer learning with convolutional neural networks for cardiovascular disease detection
This study shows the efficacy of leveraging transfer learning, specifically from residual networks, to detect CVDs and possible signs of CVDs. The findings indicate that leveraging transfer learning from residual networks alongside medical professionals is a highly promising approach for CVD detection and diagnosis, warranting further investigation.
Read More...Eye color, visual acuity and photophobia: How eye color affects light sensitivity
This study examined whether eye color affects photophobia and vision in elementary school students and staff, finding no significant relationship between eye color, light sensitivity, or visual acuity. However, photophobia was common across age groups, highlighting the need for greater awareness of light sensitivity in learning environments.
Read More...Linear relationship between nanostructural features and coloring of biomimetic photonic material
Iridescent materials reflect different colored depending on viewing angle. This specific effect can be achieved by biomimetic photonic materials. This project models the quantitative relationship between these material’s coloring and its nanostructure to facilitate personalized design of art materials.
Read More...A five-year retrospective analysis of Tuberculosis risk factors and their variability in the United States
The main goal of this study is to determine what demographics are related to tuberculosis incidence in the United States populations, particularly if changing demographics are related to differences in tuberculosis risk over two discrete time periods. The major finding is that in the two studied time periods, tuberculosis risk factors were somewhat consistent and may be influenced by things such as immigration, healthcare access, and race or ethnicity, although the top predictor did change.
Read More...AI-designed mini-protein targeting claudin-5 to enhance blood–brain barrier integrity
The authors employ computational protein design to identify a mini-protein with the potential to enhance binding of the tight junction protein, claudin-5, at the blood-blood barrier with therapeutic potential for neurodegenerative diseases.
Read More...Predicting sickle cell vaso-occlusion by microscopic imaging and modeling
The authors use blood smears from individuals with sickle cell disease to correlate sickle cell frequency with the occurrence of vaso-occlusive crises.
Read More...Enhanced soil fertility through seaweed-derived biochar: A comparative analysis with commercial fertilizers
The study explored converting Gracilaria seaweed waste—known for releasing toxic hydrogen sulfide when decomposed—into biochar as a sustainable solution for waste management and soil improvement.
Read More...A potential enzymatic pathway for polystyrene degradation using saliva of greater wax moth Galleria mellonella
Investigation of the potential of waxworm saliva, the secretion of Galleria mellonella, for plastic degradation.
Read More...In silico screening of DEAB analogues as ALDH1 isoenzymes inhibitors in cancer treatment
The authors computationally screened potential ALDH1 inhibitors, for use as potential cancer therapeutics.
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