Browse Articles

This study uses a fruit fly model of type 1 diabetes (T1D) to determine whether strengthening intestinal tight junctions to reduce intestinal permeability would improve T1D symptoms.

Understanding how bacteria respond to other bacteria could facilitate their ability to initiate and maintain their infectiousness. The phenomenon by which bacteria signal to each other via chemical signals is called quorum sensing, which could be targeted to deter bacterial infection in some cases if better understood. In this article, the authors study how a bacterium called V. fischeri uses quorum sensing to change bioluminescence, an easy readout that facilitates studying quorum sensing in this strain.

The authors assess a genetic variant within a well-known interaction partner of huntingtin that has been linked to modifying the age of onset of Huntington's disease.

The authors looked at the impact of vitamin A (retinol) on growth of S. epidermidis (most abundant bacterium on the skin) and E. coli (found in the gut microbiome, but not on the skin).

This paper investigates the potential anticancer properties of Uvularia perfoliata by testing its effects on the viability of uveal melanoma cells.

The authors test potential anti-inflammatory and pro-apoptotic effects of a polyherbal extract formulation on cultured breast cancer cells.

In this article the authors created an interaction map of proteins involved in colorectal cancer to look for driver vs. non-driver genes. That is they wanted to see if they could determine what genes are more likely to drive the development and progression in colorectal cancer and which are present in altered states but not necessarily driving disease progression.

The authors investigate whether human blood cancers carrying mutations in DNA repair genes possess increased sensitivity to common chemotherapy drugs cisplatin or gemcitabine.

The authors seek to accelerate wound healing by reducing inflammation with a cocktail containing growth factors and bioactive modulators.

The Wnt signaling pathway, known to coordinate important aspects of cellular homeostasis ranging from differentiation, proliferation, migration, and much more, is dysregulated in many human diseases. This study demonstrates that aminomethylphosphonic acid, which is the main metabolite found in the common herbicide Glyphosate, is toxic to planaria and capable of binding to canonical Wnt proteins.