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Global trends in total cholesterol by gender (1980-2018)

Qi et al. | Aug 24, 2026

Global trends in total cholesterol by gender (1980-2018)

This study explores global trends in average total cholesterol levels among adults from 1980 to 2018, finding a significant decline in both men and women, with a sharper decrease among men. While these improvements likely reflect advances in public health and medical treatment, the persistent gender gap highlights the need for more targeted approaches to cardiovascular disease prevention.

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Legacy mercury, reservoir dynamics, and dredging effects on methylmercury in San Francisco Bay

Silver et al. | Aug 24, 2026

Legacy mercury, reservoir dynamics, and dredging effects on methylmercury in San Francisco Bay

This study analyzes over two decades of monitoring data (1999-2022) to investigate how legacy mining, reservoir water releases, and dredging activities influence toxic methylmercury (MeHg) levels in San Francisco Bay. The findings reveal a significant delayed correlation between river flow and San Francisco Bay MeHg, and counter to the authors' hypothesis, a strong association between increased MeHg concentrations in the bay and both total annual dredging volume and beneficial sediment reuse / upland sediment disposal.

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Integrated expression, mutation, and survival analysis of 17 key genes in breast cancer using TCGA-BRCA data

Wang et al. | Aug 06, 2026

Integrated expression, mutation, and survival analysis of 17 key genes in breast cancer using TCGA-BRCA data

This study combines gene expression, mutation profiling, and survival analysis of 17 clinically important genes in breast cancer, utilizing the TCGA-BRCA dataset. Our results show that there are different patterns of oncogene upregulation, different levels of tumor suppressor activity, and complicated survival associations. TP53 was the most frequently mutated gene in this cohort. The results underscore the significance of multidimensional genomic analyses for a comprehensive understanding of breast cancer biology and its therapeutic ramifications.

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