Bubbles! In this study, the authors investigate the effects that different materials, temperature, and distance have on the formation of water bubbles on the surface of copper and steel. They calculated mathematical relations based on the outcomes to better understand whether interstitial hydrogen present in the d-block metals form hydrogen bonds with the water bubbles to account for the structural and mechanical stability.
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On the Relationship Between Viscosity and Surface Tension
Surface tension and viscosity are both measures of how "sticky" a liquid is, but are they related? The authors here investigate the surface tension and viscosity of mixtures of water with different concentrations of agar agar, flour, or detergent. Surprisingly, they find that the least viscous mixtures had the strongest surface tensions, indicating that the two properties are not linked.
Read More...Optical anisotropy of crystallized vanillin thin film: the science behind the art
Microscopic beauty is hiding in common kitchen ingredients - even vanillin flavoring can be turned into mesmerizing artwork by crystallizing the vanillin and examining it under a polarizing microscope. Wang and Pang explore this hidden beauty by determining the optimal conditions to grow crystalline vanillin films and by creating computer simulations of chemical interactions between vanillin molecules.
Read More...In silico modeling of emodin’s interactions with serine/threonine kinases and chitosan derivatives
Here, through protein-ligand docking, the authors investigated the effect of the interaction of emodin with serine/threonine kinases, a subclass of kinases that is overexpressed in many cancers, which is implicated in phosphorylation cascades. Through molecular dynamics theyfound that emodin forms favorable interactions with chitosan and chitosan PEG (polyethylene glycol) copolymers, which could aid in loading drugs into nanoparticles (NPs) for targeted delivery to cancerous tissue. Both polymers demonstrated reasonable entrapment efficiencies, which encourages experimental exploration of emodin through targeted drug delivery vehicles and their anticancer activity.
Read More...The design of Benzimidazole derivatives to bind to GDP-bound K-RAS for targeted cancer therapy
In this study, the authors looked at a proto-oncogene, KRAS, and searched for molecules that are predicted to be able to bind to the inactive form of KRAS. They found that a modified version of Irbesartan, a derivative of benzimidazole, showed the best binding to inactive KRAS.
Read More...Hydrogen Sulfide Inhibits Flowering but Hastens New Leaf Growth in Bok Choy (Chinese Cabbage)
Hydrogen sulfide is toxic at high concentrations, but at low concentrations may be helpful for plant growth. This study characterizes the effect of hydrogen sulfide exposure on leafy plant growth. Bok choy hearts were grown in the presence of hydrogen sulfide, and measured for new leaf growth and flowering.
Read More...Investigating Hydrogen as a Potential Alternative to Kerosene in Fueling Commercial Aircraft
Growing climate concerns have intensified research into zero-emission transportation fuels, notably hydrogen. Hydrogen is considered a clean fuel because its only major by-product is water. This project analyzes how hydrogen compares to kerosene as a commercial aircraft fuel with respect to cost, CO2 emissions, and flight range.
Read More...The Effect of Antioxidant Vitamins on Mustard Plants in a Hydrogen Peroxide-Induced Injury Model
In this study, the authors assess the antioxidant properties of vitamins A, C and E given to mustard plants after oxidative damage. This research shows an interesting comparison of the vitamins' effect on plant recovery and health.
Read More...How Ethanol Concentration Affects Catalase Catalysis of Hydrogen Peroxide
Catalase is a critical enzyme in the human body because it is capable of converting potentially dangerous hydrogen peroxide into water and oxygen. This work asks whether ethanol affects catalase activity, as alcohol consumption has been often linked to hepatitis occurring in the liver, where catalase level is especially high, and ethanol is known to be capable of denaturing proteins. Testing different concentrations of ethanol found that higher concentrations reduced the activity of catalase. This work has important implications on the negative effects of ethanol on metabolism, in which catalase plays an important role, and protein function more broadly.
Read More...Racemic serine is less soluble than pure enantiomers due to stronger intermolecular hydrogen bonds
Seeking to develop a better understanding of the chemical and physical properties of amino acids that compose proteins, here the authors investigated the unusual relative insolubility of racemic mixtures of D- and L-serine compared to the solubility of pure D- or L-serine. The authors used a combination of microscopy and temperature measurements alongside previous X-ray diffraction studies to conclude that racemic DL-serine crystals consist of comparatively stronger hydrogen bond interactions compared to crystals of pure enantiomers. These stronger interactions were found to result in the unique release of heat during the crystallization of racemic mixtures.
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