The authors computationally screened potential ALDH1 inhibitors, for use as potential cancer therapeutics.
Read More...In silico screening of DEAB analogues as ALDH1 isoenzymes inhibitors in cancer treatment
The authors computationally screened potential ALDH1 inhibitors, for use as potential cancer therapeutics.
Read More...Recombinant preparation and characterization of ADH1C and ALDH2 in alcohol metabolism
The authors test the activity of two purified human alcohol detoxification enzymes, alcohol dehydrogenase and aldehyde dehydrogenase.
Read More...Ocean, atmosphere, and cloud quantity on the surface conditions of tidally-locked habitable zone planets
The authors assessed the atmospheric and oceanic parameters necessary for tidally-locked exoplanets to be habitable.
Read More...Combating Insulin Resistance Using Medicinal Plants as a Supplementary Therapy to Metformin in 3T3-L1 Adipocytes: Improving Early Intervention-Based Diabetes Treatment
A primary cause of diabetes is insulin resistance, which is caused by disruption of insulin signal transduction. The objective of this study was to maximize insulin sensitivity by creating a more effective, early intervention-based treatment to avert severe T2D. This treatment combined metformin, “the insulin sensitizer”, and medicinal plants, curcumin, fenugreek, and nettle.
Read More...Use of yogurt bacteria as a model surrogate to compare household cleaning solutions
While resources on the safety of household cleaning products are plentiful, measures of efficacy of these cleaning chemicals against bacteria and viruses remain without standardization in the consumer market. The COVID pandemic has exasperated this knowledge gap, stoking the growth of misinformation and misuse surrounding household cleaning chemicals. Arriving at a time dire for sanitization standardization, the authors of this paper have created a quantifying framework for consumers by comparing a wide range of household cleaning products in their efficacy against bacteria generated by a safe and easily replicable yogurt model.
Read More...Flight paths over greenspace in major United States airports
Greenspaces (urban and wetland areas that contain vegetation) are beneficial to reducing pollution, while airplanes are a highly-polluting method of transportation. The authors examine the intersection of these two environmental factors by processing satellite images to reveal what percentage of flight paths go over greenspaces at major US airports.
Read More...Discovery of novel targets for diffuse large B-cell lymphoma
In this study, the authors identify new potential targets to treat advanced diffuse large B-cell lymphoma after treatment relapse and loss of CD19 expression.
Read More...Comparing Suturing And Stapling In Coronary Bypass Grafting Anastomosis
Coronary artery bypass grafts are a common technique to treat coronary heart disease. The authors compared the efficacy of suturing and stapling techniques using an artificial heart pump and silicone tubing and found that suturing, while more time and skill intensive, held pressure in the tubing better than stapling.
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