Browse Articles

Discovery of the Heart in Mathematics: Modeling the Chaotic Behaviors of Quantized Periods in the Mandelbrot Set

Golla et al. | Dec 14, 2020

Discovery of the Heart in Mathematics: Modeling the Chaotic Behaviors of Quantized Periods in the Mandelbrot Set

This study aimed to predict and explain chaotic behavior in the Mandelbrot Set, one of the world’s most popular models of fractals and exhibitors of Chaos Theory. The authors hypothesized that repeatedly iterating the Mandelbrot Set’s characteristic function would give rise to a more intricate layout of the fractal and elliptical models that predict and highlight “hotspots” of chaos through their overlaps. The positive and negative results from this study may provide a new perspective on fractals and their chaotic nature, helping to solve problems involving chaotic phenomena.

Read More...

Expression of Anti-Neurodegeneration Genes in Mutant Caenorhabditis elegans Using CRISPR-Cas9 Improves Behavior Associated With Alzheimer’s Disease

Mishra et al. | Sep 14, 2019

Expression of Anti-Neurodegeneration Genes in Mutant <em>Caenorhabditis elegans</em> Using CRISPR-Cas9 Improves Behavior Associated With Alzheimer’s Disease

Alzheimer's disease is one of the leading causes of death in the United States and is characterized by neurodegeneration. Mishra et al. wanted to understand the role of two transport proteins, LRP1 and AQP4, in the neurodegeneration of Alzheimer's disease. They used a model organism for Alzheimer's disease, the nematode C. elegans, and genetic engineering to look at whether they would see a decrease in neurodegeneration if they increased the amount of these two transport proteins. They found that the best improvements were caused by increased expression of both transport proteins, with smaller improvements when just one of the proteins is overly expressed. Their work has important implications for how we understand neurodegeneration in Alzheimer's disease and what we can do to slow or prevent the progression of the disease.

Read More...

The Effects of Altered Microbiome on Caenorhabditis elegans Egg Laying Behavior

Gohari et al. | Aug 12, 2019

The Effects of Altered Microbiome on <em>Caenorhabditis elegans</em> Egg Laying Behavior

Since the discovery that thousands of different bacteria colonize our gut, many of which are important for human wellbeing, understanding the significance of balancing the different species on the human body has been intensely researched. Untangling the complexity of the gut microbiome and establishing the effect of the various strains on human health is a challenge in many circumstances, and the need for simpler systems to improve our basic understanding of microbe-host interactions seems necessary. C. elegans are a well-established laboratory animal that feed on bacteria and can thus serve as a less complex system for studying microbe-host interactions. Here the authors investigate how the choice of bacterial diet affects worm fertility. The same approach could be applied to many different outcomes, and facilitate our understanding of how the microbes colonizing our guts affect various bodily functions.

Read More...

Pichia kudriavzevii Yeast Exposure Increases the Asthmatic Behavior of Alveolar Epithelial Cells In Vitro

Ortega et al. | Jun 07, 2019

<em>Pichia kudriavzevii</em> Yeast Exposure Increases the Asthmatic Behavior of Alveolar Epithelial Cells <em>In Vitro</em>

Asthma affects over 334 million people worldwide and is triggered by inhalation of environmental stimuli. The authors of this study characterized the effect of exposure to common spoilage yeast, Pichia kidriavzevii on alveolar epithelial cells. A direct correlation between infection duration and asthmatic status of these cells was found, indicating the potential for this yeast to be an environmental stimulus of asthma and warranting further study.

Read More...

The Long-Term Effect of CBD Crystals and CBD Oil on Depressive-Associated Rat Behaviors

Yang et al. | Dec 18, 2020

The Long-Term Effect of CBD Crystals and CBD Oil on Depressive-Associated Rat Behaviors

Cannabidiol (CBD) is a chemical extracted from cannabis and shown by some studies to alleviate the symptoms of many mental disorders, especially major depressive disorder. The authors hypothesized that chronic treatments with purified CBD through oral administration would relieve depression-associated behaviors in normal healthy rats under adverse conditions. A statistical analysis of the experimental data suggested that long-term consumption of CBD could elicit depression associated symptoms in normal rats without depression. The results imply that people should consume CBD-containing products with extreme caution and highlight the need to carefully monitor the use of CBD in health care products.

Read More...

Extroverts as Materialists: Correlating Personality Traits, Materialism, and Spending Behavior

Jackson et al. | Feb 19, 2017

Extroverts as Materialists: Correlating Personality Traits, Materialism, and Spending Behavior

The authors investigated the relationship between personality traits and adolescent materialism, as well as how materialism relates to spending habits. Results indicate that extroversion was positively correlated with materialism, and that adolescents' purchases were affected by the purchasing behaviors of their friends or peers. Moreover, materialistic youth were more likely than non-materialistic youth to spend money on themselves when given a hypothetical windfall of $500.

Read More...