Here, recognizing that the immune response to cancer results in biomarkers that can be used to assess the immune status of cancer patients, the authors investigated the concentrations of key cytokines (TH1 and TH2 cytokines) in healthy controls and cancer patients. They identified significant changes in resting and activated cytokine profiles, suggesting that data of biomarkers such as these could serve as a starting point for further treatment with regard to a patient's specific immune profile.
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A comparison study in the expansion of human bone marrow mesenchymal stem cells
In this study, the effects of different sources of serum on growing mesenchymal stem cells are compared with the goal of identifying one more suitable for clinical use.
Read More...Methanotrophic bioremediation for the degradation of oceanic methane and chlorinated hydrocarbons
Seeking an approach to address the increasing levels of methane and chlorinated hydrocarbons that threaten the environment, the authors worked to develop a novel, low-cost biotrickling filter for use as an ex situ method tailored to marine environments. By using methanotrophic bacteria in the filter, they observed methane degradation, suggesting the feasibility of chlorinated hydrocarbon degradation.
Read More...Sex differences in sleep disorders of Parkinson’s disease patients associated with a genetic risk variant
The authors use known Parkinson's disease-associated genetic variants to compare the prevalence of sleep dysfunction between males and females diagnosed with Parkinson's disease.
Read More...A HOG feature extraction and CNN approach to Parkinson’s spiral drawing diagnosis
Parkinson’s disease (PD) is a prevalent neurodegenerative disorder in the U.S., second only to Alzheimer’s disease. Current diagnostic methods are often inefficient and dependent on clinical exams. This study explored using machine and deep learning to enhance PD diagnosis by analyzing spiral drawings affected by hand tremors, a common PD symptom.
Read More...Modeling stearoyl-coenzyme A desaturase 1 inhibitors to ameliorate α-Syn cytotoxicity in Parkinson's disease
The authors use molecular modeling to test analogs of the stearoyl-coenzyme A desaturase 1 (SCD1) inhibitor MF-438 with implications for future development of Parkinson's disease therapeutics.
Read More...Predictions of neural control deficits in elders with subjective memory complaints and Alzheimer’s disease
The authors compare neuroimaging datasets to identify potential new biomarkers for earlier detection of Alzheimer's disease.
Read More...Nature’s reset: The effect of native and invasive plant forage on honey bee nutrition and survival
The authors looked at survival of honey bees over the winter in regards to native and invasive plant availability. They found that native plants provided greater survivability and overall health compared to environments where there was an abundance of invasive plants.
Read More...Motivation’s impact on high-level high school students’ ability to balance academic and athletic stress
The authors looked at the relation between stress and motivation in high school students with 4+ AP classes that also played a varsity sport. No distinct correlation was observed, however, results indicated that there are other factors at play that influence both stress and motivation.
Read More...Comparing the reducing sugars in avocados, soybeans, and cinnamon: A Benedict’s test experiment
The authors test the levels of reducing sugars in avocados, soybeans, and cinnamon as part of a diet for individuals managing Type II diabetes.
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