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Elevated acetylcholinesterase (AChE) activity contributes to cognitive decline and neurodegenerative diseases such as Alzheimer’s, motivating the search for more effective inhibitors with better bioavailability. This study used computational methods to design novel, non-toxic AChE inhibitors.

Iridescent materials reflect different colored depending on viewing angle. This specific effect can be achieved by biomimetic photonic materials. This project models the quantitative relationship between these material’s coloring and its nanostructure to facilitate personalized design of art materials.

This study examined how social determinants of health (SDH) relate to vision loss by analyzing publicly available data from 18 northern and southern U.S. states and using Bayesian correlation analysis.

The authors looked at using computer vision to evaluate the degree of exotropia in individuals with strabismus.

Analysis of the Sloan green and red photometry of the Type Ia supernova 2024neh

The authors explored the effects of the Mount Laurel Doctrine on housing affordability, unemployment rate, and civilian labor force in Burlington County, New Jersey compared to nearby counties.

Semiconductors are the center of the fourth industrial revolution as they are key components for all electronics. Exposed wafers made of silicon (Si), which can easily oxidize, convert to silicon dioxide (SiO₂). The surface of SiO₂ wafers consists of many Si-OH bonds, allowing them to easily bond with water, resulting in a “wet” or hydrophilic condition. We sought to determine a way to modify the surface of SiO₂ wafers to become hydrophobic to ensure safe wet cleaning.

Observing transients like supernovae, which have short-lived brightness variations, helps astronomers understand cosmic phenomena. This study analyzed transient 2023jri, hypothesizing it was a Type IIb supernova. By collecting and analyzing data over four weeks, including light and color curves, they confirmed its classification and provided additional insights into this less-studied supernova type.

The authors use molecular modeling to test analogs of the stearoyl-coenzyme A desaturase 1 (SCD1) inhibitor MF-438 with implications for future development of Parkinson's disease therapeutics.

The authors looked at 5-FU resistant HeLa cells and the ability of an herbal extract to show anti-inflammatory properties.