In this study, the authors identify new potential targets to treat advanced diffuse large B-cell lymphoma after treatment relapse and loss of CD19 expression.
Read More...Discovery of novel targets for diffuse large B-cell lymphoma
In this study, the authors identify new potential targets to treat advanced diffuse large B-cell lymphoma after treatment relapse and loss of CD19 expression.
Read More...The Effect of Wind Mitigation Devices on Gabled Roofs
The purpose of this study was to test devices installed on a gabled roof to see which reduced the actual uplift forces best. Three gabled birdhouse roofs were each modified with different mitigation devices: a rounded edge, a barrier shape, or an airfoil. The barrier edge had no significant effect on the time for the roof to blow off. The addition of airfoil devices on roofs, specifically in areas that are prone to hurricanes such as Florida, could keep roofs in place during hurricanes, thus reducing insurance bills, overall damage costs, and the loss of lives.
Read More...Testing Epoxy Strength: The High Strength Claims of Selleys’s Araldite Epoxy Glues
Understanding the techniques used to improve the adhesion strength of the epoxy resin is important especially for consumer applications such as repairing car parts, bonding aluminum sheeting, and repairing furniture or applications within the aviation or civil industry. Selleys Araldite epoxy makes specific strength claims emphasizing that the load or weight that can be supported by the adhesive is 72 kg/cm2. Nguyen and Clarke aimed to test the strength claims of Selley’s Araldite Epoxy by gluing two steel adhesion surfaces: a steel tube and bracket. Results showed that there is a lack of consideration by Selleys for adhesion loss mechanisms and environmental factors when accounting for consumer use of the product leading to disputable claims.
Read More...Silver armor against bacteria: A battle of antimicrobial effectiveness
Pathogenic bacteria cause major economic losses in agriculture, and widespread antibiotic use has led to increasing resistance. This study tested whether a low-cost DIY method could produce antibacterial colloidal silver effective against both Gram-negative and Gram-positive plant pathogens.
Read More...Relationship between p62 and learning behavior in male and female mice deficient in hippocampal folliculin
Here the authors hypothesized that reducing folliculin (FLCN) might affect p62 protein levels in the dorsal hippocampus of mice, given their potential functional connection and p62's role in neurodegenerative diseases. Their study, using western blots and a two-way ANOVA on young wild-type mice, found that p62 levels correlated with FLCN expression, but ultimately concluded there's no evidence of a functional connection between FLCN and p62 in this specific model.
Read More...Redefining and advancing tree disease diagnosis through VOC emission measurements
Here the authors investigated the use of an affordable gas sensor to detect volatile organic compound (VOC) emissions as an early indicator of tree disease, finding statistically significant differences in VOCs between diseased and non-diseased ash, beech, and maple trees. They suggest this sensor has potential for widespread early disease detection, but call for further research with larger sample sizes and diverse locations.
Read More...Examining the correlation between Massa Medicata Fermentata and Crohn’s disease: Implications for treatment and patient safety
Crohn’s disease is a chronic inflammatory bowel condition with symptoms like abdominal pain, fatigue, diarrhea, and malnutrition. Though there's no cure, various treatments help manage it. This study explored the potential impact of Massa Medicata Fermentata (MMF), a fermented Chinese herbal medicine containing Saccharomyces cerevisiae, on Crohn’s disease.
Read More...Initiating astrocyte to neuron transdifferentiation via miR-124a: implications in neurodegenerative disease
The authors looked at whether they could induce the formation of new neurons from astrocytes via the upregulation of a microRNA (miR-124a). They found that upregulation of miR-124a started transdifferentiation of neurons, but was not enough to lead to full conversion of astrocytes to neurons.
Read More...Nature’s reset: The effect of native and invasive plant forage on honey bee nutrition and survival
The authors looked at survival of honey bees over the winter in regards to native and invasive plant availability. They found that native plants provided greater survivability and overall health compared to environments where there was an abundance of invasive plants.
Read More...Effect of different cooking methods on the levels of iron and ascorbic acid in green vegetables
This study compares different methods for cooking vegetables to determine which retain iron and ascorbic acid, or vitamin C, levels the most.
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