Browse Articles

This study analyzes genetic alterations and expression patterns of protein kinases involved in phagocytosis across multiple cancers using TCGA data.

The authors looked how different working conditions impacted the microbiome of the human skin.

Oligodendrocytes are specialized brain cells that can change to cells that produce myelin and protect nerves. This study investigates the capacity for different extracellular matrix cues to induce this effect in culture.

Acquired immunodeficiency syndrome (AIDS) is a life-threatening condition caused by the human immunodeficiency virus (HIV). In this work, Takemaru et al explored the role of Coiled-Coil Domain-Containing 11 (CCDC11) in HIV-1 budding. Their results suggest that CCDC11 is critical for efficient HIV-1 budding, potentially indicating CCDC11 a viable target for antiviral therapeutics without major side effects.

Mesenchymal stem cells(MSCs) play a role in tumor formation by differentiating into cancer associated fibroblasts (CAFs) which enable metastasis of tumors. The process of conversion of MSCs into CAFs is not clear. In this study, authors tested the hypothesis that cancers cells secrete soluble factors that induce differentiation by culturing bone marrow mesenchymal stem cells in media conditioned by a breast cancer cell line.

The authors investigate the negative effects stress has on teen mental and physical health. Through a survey, they give Virginia teens a voice in revising the Health and Physical Education curriculum to include a standards of learning (SOL). Notably they identify factors contributing to stress levels including homework level, amount of free and sleep time, parental pressure and family encouragement.

Dental resins can be a source of reactive oxygen species (ROS) which in unruly amounts can be toxic to cellular and overall health. In this report, the authors test whether the consumption of antioxidant rich foods like avocado and asparagus can protect against the effect of dental resin-derived ROS. However, rather than testing humans, they use fruit flies and their climbing abilities as an experimental readout.

The explored the potential of an epitope-based vaccine for Rocio virus using computational methods and M13 bacteriophage technology. Researchers identified 30 promising B- and T-cell epitopes and designed vaccine candidates using both phage display and E. coli expression systems.

The authors looked at genes and pathways that are enriched in glioblastoma multiforme.

Due to a critical shortage of donor hearts, researchers are exploring cardiac xenotransplantation—transplanting animal hearts into humans—as a potential solution. This study synthesized nearly two decades of preclinical research to evaluate multiple factors affecting xenograft survival.