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Molecules which bind to proteins that aggregate abnormally in neurodegenerative diseases could be promising drugs for these diseases. In this study, Zhang, Wu, Zhang, and Dang simulate the binding behavior of various molecules to screen for candidates which could be promising candidates for drug development.

Here, seeking to identify a possible explanation for the more frequent diagnosis of autism spectrum disorder (ASD) in males than females, they sought to investigate a potential sex bias in the expression of ASD-associated genes. Based on their analysis, they identified 17 ASD-associated candidate genes that showed stronger collective sex-dependent expression.

The authors develop a new method for training machine learning algorithms to differentiate between hate speech and cultural speech in online platforms.

The authors test the effects of the pesticide captan on the growth of gut microbiome bacteria including Bacillus coagulan and Escherichia coli.

Reinforcement learning (RL) is a form of machine learning that can be harnessed to develop artificial intelligence by exposing the intelligence to multiple generations of data. The study demonstrates how reply buffer reward mechanics can inform the creation of new pruning methods to improve RL efficiency.

Spinal degeneration has been linked to critical conditions such as osteoarthritis in adults aged 40+; while this condition is considered to be irreversible, we took interest in magnetic resonance imaging (MRI) for early detection of the condition. Ultimately, our purpose was to determine the effectiveness of a relatively novel T1rho method in the early detection of spinal degeneration, and we hypothesized that the early to mild progression of spinal degeneration would affect T1rho values following an MRI scan.

The authors look at using publicly available data and machine learning to see if they can develop a criminal activity index for counties within the state of California.

In this study the authors looked at developing a more efficient particle collision classification method with the goal of being able to more efficiently analyze particle trajectories from large-scale particle collisions without loss of accuracy.

This article describes the relationship between socioeconomic factors and the extent of how the COVID-19 Pandemic affected communities. Factors such as infection rate, vaccination rate, and economic status were all evaluated within the context of this article.

A bottleneck in deleting algal blooms is that current data section is manual and is reactionary to an existing algal bloom. These authors made a custom-designed Seek and Destroy Algal Mitigation System (SDAMS) that detects harmful algal blooms at earlier time points with astonishing accuracy, and can instantaneously suppress the pre-bloom algal population.