Cell segmentation is the task of identifying cell nuclei instances in fluorescence microscopy images. The goal of this paper is to benchmark the performance of representative deep learning techniques for cell nuclei segmentation using standard datasets and common evaluation criteria. This research establishes an important baseline for cell nuclei segmentation, enabling researchers to continually refine and deploy neural models for real-world clinical applications.
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Sepia bandensis ink inhibits polymerase chain reactions
While cephalopods play significant roles in both ecosystems and medical research, there is currently no assembled genome. In an attempt to sequence the Sepia bandensis genome, it was found that there was inhibition from the organism during DNA extraction, resulting in PCR failure. In this study, researchers tested the hypothesis that S. bandensis ink inhibits PCR. They then assessed the impact of ink on multiple methods of DNA extraction
Read More...Investigating the inhibition of catabolic enzymes for implications in cardiovascular diseases and diabetes
Enzymes that metabolize carbohydrates and lipids play a key role in our health, including global health challenges like cardiovascular diseases and diabetes. To learn more about these important enzymes, Gandhi and Gandhi test whether various natural substances (ginger, Aloe vera, lemon, and mint leaves) affect the activity of α-amylase and lipase enzymes.
Read More...Using broad health-related survey questions to predict the presence of coronary heart disease
Coronary heart disease (CHD) is the leading cause of death in the U.S., responsible for nearly 700,000 deaths in 2021, and is marked by artery clogging that can lead to heart attacks. Traditional prediction methods require expensive clinical tests, but a new study explores using machine learning on demographic, clinical, and behavioral survey data to predict CHD.
Read More...Identifying factors, such as low sleep quality, that predict suicidal thoughts using machine learning
Sadly, around 800,000 people die by suicide worldwide each year. Dong and Pearce analyze health survey data to identify associations between suicidal ideation and relevant variables, such as sleep quality, hopelessness, and anxious behavior.
Read More...Simulating natural selection via autonomous agents: Environmental factors create unstable equilibria
Natural selection shapes the evolution of all organisms, and one question of interest is whether natural selection will reach a "stopping point": a stable, ideal, value for any particular trait. Madhan and Kanagavel tackle this question by building a computer simulation of trait evolution in organisms.
Read More...Analysis of biofertilization impacts on Pisum sativum
This study explored the various effects of three different produce-based biofertilizers on pea plant growth, using red apple, pear, strawberry, and control treatments. It was hypothesized that the application of fruit biomatter would increase the growth of pea plants, with the application of strawberry biomatter having the most significant effect due to strawberries containing a higher nutrient content compared to pears and apples. Analysis confirmed the hypothesis. The application of strawberry biomatter could prove to be an effective way to increase plant growth in commercial agriculture.
Read More...Analysis of professional and amateur tennis serves using computer pose detection
The authors looked at the dynamics of tennis serves from professional and amateur athletes.
Read More...A new hybrid cold storage material
With low-temperature transportation being critical for the progress of research and medical services by preserving biological samples and vaccines, the optimization of cold storage materials is more critical now than ever. The exclusive use of dry ice has its limitations. Notably, it proves insufficient for cold storage during long-range transportation necessary for the delivery of specimens to rural areas. In this article, the authors have proposed a new means of cold storage through the combination of dry ice and ethanol. Upon thorough analysis, the authors have determined their new method as considerably better than the use of pure dry ice across many characteristics, including cold storage capacity, longevity of material, and financial and environmental feasibility.
Read More...A novel approach to determine which organism best displays Gijswijt's Sequence in its genome
The sequence of nitrogenous bases that make up the DNA of organisms can contain hidden mathematical sequences. Here the authors used BioPython, a programming tool, to find an organism that displays Gijswijt’s Sequence in its genome. In this manner they found that the common carp best displays Gijswijt’s Sequence in its genome.
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