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Polo-like kinase 1 (Plk1) is a master regulator of mitosis, initiating key steps of cell cycle regulation, and its overexpression is associated with certain types of cancer. In this study, the authors carefully designed peptides that were able to bind to Plk1 at a location that is important for its proper localization and function. Future studies could further develop these peptides to selectively target Plk1 in cancer cells and induce mitotic arrest.

Detecting cervical spondylosis using deep learning

The authors looked at how the length of an audio clip used of a song impacted the ability to properly classify it by musical genre.

Crohn’s disease is a chronic inflammatory bowel condition with symptoms like abdominal pain, fatigue, diarrhea, and malnutrition. Though there's no cure, various treatments help manage it. This study explored the potential impact of Massa Medicata Fermentata (MMF), a fermented Chinese herbal medicine containing Saccharomyces cerevisiae, on Crohn’s disease.

The authors compare current machine learning algorithms with a new Explainable AI algorithm that produces a human-comprehensible decision tree alongside predictions.

The authors looked at non-natural factors that influenced the spread rate of fire ants in multiple cities in China.

Here the authors present an autonomous drone air filtration system that uses a novel algorithm, the gradient ascent ML particle filter (GA/MLPF), to efficiently locate and mitigate outdoor air pollution. They demonstrate that their GA/MLPF algorithm is significantly more efficient than the conventional gradient ascent algorithm, reducing both the time and number of waypoints needed to find the source of pollution.

The authors looked at the immunogenicity of a newly developed pneumococcal conjugate vaccine compared to a previously developed one. They found the newly developed vaccine did elicit an immune response.

The authors looked at how storage temperature of potatoes can impact the sweetness of potatoes (due to the break down of the starch into simple sugars).

The escalating crisis of climate change, driven by the accumulation of greenhouse gases from human activities, demands urgent and innovative solutions to curb rising global temperatures. Plasma-based methane (CH₄) and carbon dioxide (CO₂) reforming offers a promising pathway for carbon capture and the sustainable production of hydrogen fuel and syngas components. To advance this technology, particularly in terms of energy efficiency and selectivity, it is essential to enhance the conversion efficiencies of CO₂ and CH₄.