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Wound healing properties of mesenchymal conditioned media: Analysis of PDGF, VEGF and IL-8 concentrations

Prasad et al. | Dec 15, 2021

Wound healing properties of mesenchymal conditioned media: Analysis of PDGF, VEGF and IL-8 concentrations

Regenerative medicine has become a mainstay in recent times, and employing stem cells to treat several degenerative, inflammatory conditions has resulted in very promising outcomes. These forms of cell-based therapies are novel approaches to existing treatment modalities. In this study, the authors compared the concentrations of the cytokines PDGF, IL-8, and VEGF between conditioned and spent media of mesenchymal stem cells (MSCs) to evaluate their potential therapeutic properties for wound healing in inflammatory conditions. They hypothesized that conditioned media contains higher concentrations of wound healing cytokines compared to spent media. The authors found that while IL-8 and VEGF were present in highest concentrations in conditioned media, PDGF was present in maximal amounts in spent media.

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Characterization of Drought Tolerance in Arabidopsis Mutant fry1-6

Kim et al. | Jan 07, 2019

Characterization of Drought Tolerance in Arabidopsis Mutant  fry1-6

In a world where water shortage is becoming an increasing concern, and where population increase seems inevitable, food shortage is an overwhelming concern for many. In this paper, the authors aim to characterize a drought-resistant strain of A. thaliana, investigating the cause for its water resistance. These and similar studies help us learn how plants could be engineered to improve their ability to flourish in a changing climate.

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Estimation of cytokines in PHA-activated mononuclear cells isolated from human peripheral and cord blood

Subbiah et al. | Mar 09, 2022

Estimation of cytokines in PHA-activated mononuclear cells isolated from human peripheral and cord blood

In this study, the authors investigated the time-dependent cytokine secretion ability of phyto-hemagglutinin (PHA)-activated T cells derived from human peripheral (PB) and cord blood (CB). They hypothesized that the anti-inflammatory cytokine, IL-10, and pro-inflammatory cytokine, TNFα, levels would be higher in PHA-activated T cells obtained from PB as compared to the levels obtained from CB and would decrease over time. Upon PHA-activation, the IL-10 levels were relatively high while the TNFα levels decreased, making these findings applicable in therapeutic treatments e.g., rheumatoid arthritis, psoriasis, and organ transplantation.

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Exploring Unconventional Growing Methods to Promote Healthy Growth in Common Household Plants: Tagetes patula L. and Lepidium sativum

Nguyen et al. | Feb 25, 2021

Exploring Unconventional Growing Methods to Promote Healthy Growth in Common Household Plants: <i>Tagetes patula</i> L. and <i>Lepidium sativum</i>

This study focused on finding more sustainable growing methods that reduce chemical fertilizer or water usage and can be used at the household level for garden plants. Metrics for healthy plant growth were height at first bloom, growing time, and survival rate. The Deep Water Culture (DWC) treatment for garden cress plants significantly increased the height at first bloom compared to the control group. For rates of surviving plants, the treatments had little effect on garden cress, but the Eggshell Grounds, Wick System, and DWC system groups outperformed the control group for marigolds.

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Pichia kudriavzevii Yeast Exposure Increases the Asthmatic Behavior of Alveolar Epithelial Cells In Vitro

Ortega et al. | Jun 07, 2019

<em>Pichia kudriavzevii</em> Yeast Exposure Increases the Asthmatic Behavior of Alveolar Epithelial Cells <em>In Vitro</em>

Asthma affects over 334 million people worldwide and is triggered by inhalation of environmental stimuli. The authors of this study characterized the effect of exposure to common spoilage yeast, Pichia kidriavzevii on alveolar epithelial cells. A direct correlation between infection duration and asthmatic status of these cells was found, indicating the potential for this yeast to be an environmental stimulus of asthma and warranting further study.

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Dune flora can emerge from seed islands (Concon, Chile)

Farías Giusti-Bilz et al. | Dec 07, 2020

Dune flora can emerge from seed islands (Concon, Chile)

In the field of ecology, little is known about how plant communities originate. Through the process of characterizing dunes, mounds of sand formed by the wind, and their plant communities we can get to know the physiognomy and floristic composition of the territory. Based on the hypothesis that dune flora can emerge from seed islands: holes in the sand 6 cm deep containing a mixture of seeds, broken branches of shrubbery, and rabbit feces, during spring, the authors determined the composition of 20 seed islands in the sand dunes of Concon, Chile and measured how many seeds germinated in each one.

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An Analysis on Exoplanets and How They are Affected by Different Factors in Their Star Systems

Selph et al. | Dec 06, 2018

An Analysis on Exoplanets and How They are Affected by Different Factors in Their Star Systems

In this article, the authors systematically study whether the type of a star is correlated with the number of planets it can support. Their study shows that medium-sized stars are likely to support more than one planet, just like the case in our solar system. They predict that, of the hundreds of planets beyond our solar system, 6% might be habitable. As humans work to travel further and further into space, some of those might truly be suited for human life.

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The Effect of Various Liquid Mediums on the Transport of Photonic Energy and its Impact on the Quantum Efficiency of Photovoltaic Cells

Payra et al. | May 05, 2015

The Effect of Various Liquid Mediums on the Transport of Photonic Energy and its Impact on the Quantum Efficiency of Photovoltaic Cells

A photovoltaic cell (PV cell), or solar cell, converts the energy of light into electricity and is the basis for solar power. In order to increase the efficiency of PV cells, the authors in this study used common household items as photon transmissions mediums and measured their effects on the temperature and voltage output of the PV cells.

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