The goal of this project was to assess the relationships among low myopia, behavioral and demographic factors, and a single-nucleotide polymorphism (SNP) in the TGFβ1 gene.
Read More...TGFβ1 Codon 10 Polymorphism and its Association with the Prevalence of Low Myopia
The goal of this project was to assess the relationships among low myopia, behavioral and demographic factors, and a single-nucleotide polymorphism (SNP) in the TGFβ1 gene.
Read More...Analyzing the effects of genetic mutations in BRCA1, BRCA2, BARD1, and MLH1 in causing different cancers
This paper utilizes multiple publicly available cancer datasets to explore the abundance of different genetic dependencies across various cancer types. They explore this by looking at four genes highly associated with cancer and their genetic and pathogenic relationships.
Read More...VISTA inhibitor CA170 combined with KRAS vaccine enhances immune response in lung cancer
Here the authors investigated a combination therapy to target the Kirsten rat sarcoma viral oncogene homolog mutation in lung cancer, by analyzing publicly available data. Their findings indicate that the combination therapy of CA170 and Kvax enhances helper T cell function and improves cytotoxic T lymphocyte infiltration, while Kvax alone drives plasma and memory B cell proliferation.
Read More...Initiating astrocyte to neuron transdifferentiation via miR-124a: implications in neurodegenerative disease
The authors looked at whether they could induce the formation of new neurons from astrocytes via the upregulation of a microRNA (miR-124a). They found that upregulation of miR-124a started transdifferentiation of neurons, but was not enough to lead to full conversion of astrocytes to neurons.
Read More...Designing gRNAs to reduce the expression of the DMPK gene in patients with classic myotonic dystrophy
The authors describe the design and testing of new guide RNAs targeting the DMPK gene, which is responsible for myotonic dystrophy.
Read More...Investigating the potential of zinc oxide nanoparticles and zinc ions as promising approaches to lung cancer
Here, the authors chose to investigate the efficacy of zinc oxide nanoparticles (ZnO NPs) and cisplatin or zinc ions in inducing cancer apoptosis. While both treatments were found to reduce the proliferation of lung cancer cells, the authors suggest that further studies to identify the mechanism are necessary.
Read More...Are Asian foods healthier than Western foods: Evidence collected from St. Louis area grocery stores
The authors compare nutritional content of foods found in Western versus Asian grocery stores to determine whether one cultural diet is healthier than the other.
Read More...Sex differences in linear polyubiquitination in the entorhinal cortex during fear memory formation
The authors explore sex-specific differences in the formation of fear memories across several rat brain regions.
Read More...Solving a new NP-Complete problem that resembles image pattern recognition using deep learning
In this study, the authors tested the ability and accuracy of a neural net to identify patterns in complex number matrices.
Read More...The sweetened actualities of neural membrane proteins: A computational structural analysis
Here, seeking to better understand the roles of glycans in the receptors of active sites of neuronal cells, the authors used molecular dynamics simulations to to uncover the dynamic nature of N-glycans on membrane proteins. The authors suggest the study of theinteractions of these membrane poreins could provide future potential therapeutic targets to treat mental diseases.
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