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The Effects of Ultraviolet Light on Escherichia coli

Kodoth et al. | Sep 07, 2015

The Effects of Ultraviolet Light on <em>Escherichia coli</em>

In this study E. coli bacteria was exposed to small UV lights currently used in school laboratories to see the effect on colony growth. This project explores how UV radiation methods could be applied in common households to inhibit bacterial growth.

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Functional Network Connectivity: Possible Biomarker for Autism Spectrum Disorders (ASD)

Wang et al. | Feb 23, 2015

Functional Network Connectivity: Possible Biomarker for Autism Spectrum Disorders (ASD)

Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder and is difficult to diagnose in young children. Here magnetoencephalography was used to compare the brain activity in patients with ASD to patients in a control group. The results show that patients with ASD have a high level of activity in different areas of the brain than those in the control group.

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Varying Growth Hormone Levels in Chondrocytes Increases Proliferation Rate and Collagen Production by a Direct Pathway

Bennett et al. | Sep 03, 2019

Varying Growth Hormone Levels in Chondrocytes Increases Proliferation Rate and Collagen Production by a Direct Pathway

Bennett and Joykutty test whether growth hormone directly or indirectly affected the rate at which cartilage renewed itself. Growth hormone could exert a direct effect on cartilage or chondrocytes by modifying the expression of different genes, whereas an indirect effect would come from growth hormone stimulating insulin-like growth factor. The results from this research support the hypothesis that growth hormone increases proliferation rate using the direct pathway. This research can be used in the medical sciences for people who suffer from joint damage and other cartilage-related diseases, since the results demonstrated conditions that lead to increased proliferation of chondrocytes. These combined results could be applied in a clinical setting with the goal of allowing patient cartilage to renew itself at a faster pace, therefore keeping those patients out of pain from these chondrocyte-related diseases.

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Nitric Oxide Synthesis/Pathway Inhibitors in Daphnia magna Reverse Alcohol-Induced Heart Rate Decrease

Gunturi et al. | Sep 17, 2019

Nitric Oxide Synthesis/Pathway Inhibitors in Daphnia magna Reverse Alcohol-Induced Heart Rate Decrease

Chronic alcohol consumption can cause cardiac myopathy, which afflicts about 500,000 Americans annually. Gunturi et al. wanted to understand the effects of alcohol on heart rate and confirm the role of nitric oxide (NO) signaling in heart rate regulation. Using the model organism Daphnia magna, a water crustacean with a large, transparent heart, they found that the heart rate of Daphnia magna was reduced after treatment with alcohol. This depression could be reversed after treatment with inhibitors of NO synthesis and signaling. Their work has important implications for how we understand alcohol-induced effects on heart rate and potential treatments to reverse heart rate depression as a result of alcohol consumption.

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Correlation of socioeconomic status and lead concentration in tap water in Missouri

Rabbani et al. | Feb 03, 2022

Correlation of socioeconomic status and lead concentration in tap water in Missouri

Organic and non-organic contaminants in tap water have been linked to adverse health effects. Tap water is a major source of lead, which is neurotoxic and poses a major health risk, particularly to children and pregnant women. Using publicly available annual water quality reports data for the state of Missouri, the authors show that communities with lower median household income and lower per capita incomes had significantly higher lead levels in their tap water.

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Cell cytotoxicity and pro-apoptosis on MCF-7 cells using polyherbal formulation, MAT20

Tarigopula et al. | Feb 17, 2023

Cell cytotoxicity and pro-apoptosis on MCF-7  cells using polyherbal formulation, MAT20

The purpose of this study was to test the anti-cancer properties and pro-apoptotic effects of the polyherbal formulation MAT20 as a complementary treatment. Moringa oleifera (Moringa), Phyllanthus emblica (Amla) and Ocimum sanctum (Tulsi), these 3 herbs were used to formulate MAT20, which contain phytochemicals that are known to display anti-cancer properties. In this study, we hypothesized that MCF-7 breast cancer cells treated with MAT20 would show increased cytotoxicity compared to its individual plant extracts.

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