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Machine learning predictions of additively manufactured alloy crack susceptibilities

Gowda et al. | Nov 12, 2024

Machine learning predictions of additively manufactured alloy crack susceptibilities

Additive manufacturing (AM) is transforming the production of complex metal parts, but challenges like internal cracking can arise, particularly in critical sectors such as aerospace and automotive. Traditional methods to assess cracking susceptibility are costly and time-consuming, prompting the use of machine learning (ML) for more efficient predictions. This study developed a multi-model ML pipeline that predicts solidification cracking susceptibility (SCS) more accurately by considering secondary alloy properties alongside composition, with Random Forest models showing the best performance, highlighting a promising direction for future research into SCS quantification.

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The use of computer vision to differentiate valley fever from lung cancer via CT scans of nodules

El Kereamy et al. | Nov 12, 2024

The use of computer vision to differentiate valley fever from lung cancer via CT scans of nodules

Pulmonary diseases like lung cancer and valley fever pose serious health challenges, making accurate and rapid diagnostics essential. This study developed a MATLAB-based software tool that uses computer vision techniques to differentiate between these diseases by analyzing features of lung nodules in CT scans, achieving higher precision than traditional methods.

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pH-dependent drug interactions with acid reducing agents

Lin et al. | Nov 12, 2024

pH-dependent drug interactions with acid reducing agents
Image credit: The authors

Some cancer treatments lose efficacy when combined with treatments for excessive stomach acid, due to the changes in the stomach environment caused by the stomach acid treatments. Lin and Lin investigate information on oral cancer drugs to see what information is available on interactions of these drugs.

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A meta-analysis on NIST post-quantum cryptographic primitive finalists

Benny et al. | Sep 21, 2024

A meta-analysis on NIST post-quantum cryptographic primitive finalists
Image credit: Benny et al. 2024

The advent of quantum computing will pose a substantial threat to the security of classical cryptographic methods, which could become vulnerable to quantum-based attacks. In response to this impending challenge, the field of post-quantum cryptography has emerged, aiming to develop algorithms that can withstand the computational power of quantum computers. This study addressed the pressing concern of classical cryptographic methods becoming vulnerable to quantum-based attacks due to the rise of quantum computing. The emergence of post-quantum cryptography has led to the development of new resistant algorithms. Our research focused on four quantum-resistant algorithms endorsed by America’s National Institute of Standards and Technology (NIST) in 2022: CRYSTALS-Kyber, CRYSTALS-Dilithium, FALCON, and SPHINCS+. This study evaluated the security, performance, and comparative attributes of the four algorithms, considering factors such as key size, encryption/decryption speed, and complexity. Comparative analyses against each other and existing quantum-resistant algorithms provided insights into the strengths and weaknesses of each program. This research explored potential applications and future directions in the realm of quantum-resistant cryptography. Our findings concluded that the NIST algorithms were substantially more effective and efficient compared to classical cryptographic algorithms. Ultimately, this work underscored the need to adapt cryptographic techniques in the face of advancing quantum computing capabilities, offering valuable insights for researchers and practitioners in the field. Implementing NIST-endorsed quantum-resistant algorithms substantially reduced the vulnerability of cryptographic systems to quantum-based attacks compared to classical cryptographic methods.

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The effect of bioenhancers on ampicillin-sulbactam as a treatment against A. baumannii

Balaji et al. | Sep 21, 2024

The effect of bioenhancers on ampicillin-sulbactam as a treatment against <i>A. baumannii<i>

This article explores the potential of piperine, a bioenhancer from black pepper, to improve antibiotic efficacy against antibiotic-resistant Acinetobacter baumannii. By combining piperine with ampicillin-sulbactam, the study demonstrated a significant reduction in bacterial growth for most strains tested, showcasing the promise of bioenhancers in combating resistant pathogens. This research highlights the possibility of reducing the required antibiotic dosage, potentially offering a new strategy in the fight against drug-resistant bacteria.

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Shortage of Black physicians: Florida Black medical student enrollment from 2013 to 2021

Khan et al. | Sep 18, 2024

Shortage of Black physicians: Florida Black medical student enrollment from 2013 to 2021

Black patients tend to have better health outcomes when cared for by Black physicians, yet Black doctors make up only 5% of U.S. physicians, despite Black people comprising 14% of the population. This analysis of data from Florida medical schools showed a higher enrollment of Black first-year students (13.5%) compared to the national average (9%), and a national increase from 6% in 2013 to 9% in 2021, aligning with the rise of social justice movements. Increasing Black medical student enrollment could reduce health disparities and improve outcomes for Black communities.

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Near-infrared activation of environmentally-friendly gold and silver nanoparticles for unclogging arteries

Gill et al. | Sep 06, 2024

Near-infrared activation of environmentally-friendly gold and silver nanoparticles for unclogging arteries

Coronary artery disease, the leading cause of death worldwide, results from cholesterol build-up in coronary arteries, limiting blood and oxygen flow to the heart. This study investigated the use of gold and silver nanoparticles coated with aspirin and activated by near-infrared light to improve blood flow in a clogged artery model. The nanoparticles increased simulated blood flow rates, demonstrating potential as a less invasive and more targeted treatment for cardiovascular disease.

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