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Assessing the Efficacy of NOX Enzyme Inhibitors as Potential Treatments for Ischemic Stroke in silico

Vinay et al. | Sep 18, 2020

Assessing the Efficacy of NOX Enzyme Inhibitors as Potential Treatments for Ischemic Stroke <i>in silico</i>

Ischemic stroke occurs when blood flow to the brain is interrupted, causing brain damage. This study investigated the effectiveness of different NOX inhibitors as treatments for ischemic stroke in silico. The results help corroborate previous in vivo and in vitro studies in an in silico format, and can be used towards developing drugs to treat ischemic stroke.

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Effect of Fertilizer on Water Quality of Creeks over Time

Chen et al. | May 02, 2021

Effect of Fertilizer on Water Quality of Creeks over Time

Fertilizers are commonly used to improve agricultural yield. Unfortunately, chemical fertilizers can seep into drinking water, potentially harming humans and other forms of life. Here, the authors investigate the effect of fertilizer on the water quality of Saratoga Creek over time. They find that fertilizers can alter the acidity of the creek's water, which can be harmful to aquatic species, as well as increase the levels of nitrates temporarily.

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Combined Progestin-Estrogenic Contraceptive Pills May Promote Growth in Crop-Plants

Saha et al. | Feb 21, 2020

Combined Progestin-Estrogenic Contraceptive Pills May Promote Growth in Crop-Plants

Ethinyl estradiol and progestin norgestrel are commonly present in contraceptive tablets and it is unknown how they affect the environment. In this study, the authors investigate the role that ethinyl estradiol and progestin norgestrel have on the growth of flowering plants. The percentage germination, embryonic and adventitious tissue proliferation, root length, and shoot length were measured in V. radiata and T. aestivum treated with each compound and results demonstrate that ethinyl estradiol and progestin norgestrel can induce growth in both plants at certain concentrations. These findings have important implications as societal use of chemicals increases and more make their way into the environment.

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Is Cloud Cover One of the Effects of Climate Change?

Crair et al. | Mar 27, 2014

Is Cloud Cover One of the Effects of Climate Change?

Climate change is one of the most controversial challenges humans face. Here the authors investigate the dual role of clouds - to reflect incoming light away from the Earth and to reflect heat energy back toward the Earth's surface. They find that the amount of incident light energy and surface temperature decreases as the sky becomes cloudier. These results will inform longer-term studies that may compare against the amount of energy clouds reflect back toward the Earth.

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In vitro Comparison of Anticancer and Immunomodulatory Activities of Resveratrol and its Oligomers

Zhang et al. | Sep 02, 2020

<em>In vitro</em> Comparison of Anticancer and Immunomodulatory Activities of Resveratrol and its Oligomers

Resveratrol is a type of stillbenoid, a phenolic compound produced in plants, that is known for its anti-inflammatory and anticancer effects. Many oligomers of resveratrol have recently been isolated their bioactivities remain unknown. Here, authors compared the bioactivities of resveratrol with natural dimers (ε-viniferin and gnetin H) and trimers (suffruticosol B and C). Results provide preliminary evidence that resveratrol oligomers could be potential preventive or therapeutic agents for cancers and other immune-related diseases

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The Effect of Caffeine on the Regeneration of Brown Planaria (Dugesia tigrina)

Lazorik et al. | May 10, 2019

The Effect of Caffeine on the Regeneration of Brown Planaria (<em>Dugesia tigrina</em>)

The degeneration of nerve cells in the brain can lead to pathologies such as Parkinson’s disease. It has been suggested that neurons in humans may regenerate. In this study, the effect of different doses of caffeine on regeneration was explored in the planeria model. Caffeine has been shown to enhance dopamine production, and dopamine is found in high concentrations in regenerating planeria tissues. Higher doses of caffeine accelerated planeria regeneration following decapitation, indicating a potential role for caffeine as a treatment to stimulate regeneration.

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Development of Two New Efficient Means of Wastewater Treatment

Bao et al. | Feb 06, 2014

Development of Two New Efficient Means of Wastewater Treatment

The water we use must be treated and cleaned before we release it back into the environment. Here, the authors investigate two new techniques for purifying dissolved impurities from waste water. Their findings may give rise to more cheaper and more efficient water treatment and help keep the planet greener.

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Effects of Ocean Acidification on Marine Calcium Carbonate

Prahalad et al. | Jul 31, 2020

Effects of Ocean Acidification on Marine Calcium Carbonate

Industrialization has transformed human life and improved it for many. Nonetheless, a side effect has been an increase in chemical waste, which when not disposed of properly, has detrimental effects on surrounding habitats. An increase in ocean acidification could potentially affect many forms of life, disrupting the ecological balance in unforeseeable ways. In this article the authors explore the effect of acidification on corals and shells, and observe that an increase in ocean acidity has a significant effect on corals, but not shells. This illustrates how acidification could negatively affect marine life, and calls our attention to managing the factors that contribute to increasing the pH of the Earth's water bodies.

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