This study compares three methods regarding their accuracy in calculating the distance between the Earth and the Sun. The hypothesis presented was that the shadow method would have the greatest mean accuracy, followed by the tube pinhole method, and finally the plate pinhole method. The results validate the hypothesis; however, further investigation would be helpful in determining effective mitigation of each method’s limitations and the effectiveness of each method in determining the distance of other light-emitting objects distant from the Earth.
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Synthesis of a novel CCR1 antagonist for treatment of glioblastoma
Glioblastoma is a brain cancer caused by the presence of a fast-growing, malignant tumor in the brain. As of now, this cancer is universally lethal due to lack of efficacious treatment options. C-C chemokine receptor 1 (CCR1) is a G-protein coupled receptor that controls chemotaxis, the movement of cells in response to chemical stimuli. This research aims to synthesize potential CCR1 antagonists by coupling carboxylic acids with a triazole core. We synthesized these compounds using a simple carboxylic acid coupling and confirmed the identity of the final compounds using nuclear magnetic resonance (NMR) spectroscopy.
Read More...Alterations of the [Fe/H] Values Modulate Light Curves by Absolute Magnitude in non-Blazhko RRab Lyraes
In this study, the authors investigate the relationship between iron/hydrogen ratio [Fe/H] of a type of variable stars commonly used as reference points RR Lyrae stars and their light curves to see if one can determine the composition of these stars solely by measuring their light curve characteristics.
Read More...Enhanced soil fertility through seaweed-derived biochar: A comparative analysis with commercial fertilizers
The study explored converting Gracilaria seaweed waste—known for releasing toxic hydrogen sulfide when decomposed—into biochar as a sustainable solution for waste management and soil improvement.
Read More...The effect of music on teenagers in combatting stress and improving performance
Here, the researchers investigated how exposure to active versus passive music affects a teenager's ability to perform a challenging task, namely a Sudoku puzzle, under stressful conditions. Following testing 75 high school teenagers split into two group, the researchers found that singing in a choir (active music) yielded a greater improvement in performance compared to passive listening for brief time periods.
Read More...Transfer Learning with Convolutional Neural Network-Based Models for Skin Cancer Classification
Skin cancer is a common and potentially deadly form of cancer. This study’s purpose was to develop an automated approach for early detection for skin cancer. We hypothesized that convolutional neural network-based models using transfer learning could accurately differentiate between benign and malignant moles using natural images of human skin.
Read More...Floor level estimation using MEMS pressure sensors
The authors propose a method to help first responders find the location of a person within a high-rise building in densely populated areas.
Read More...The Effects of Various Plastic Pollutants on the Growth of the Wisconsin Fast Plant
Here the authors investigate the effects of plastic pollutants on terrestrial life. Specifically they look at the growth of Brassica rapa and determine that phosphate levels have the most negative impact on growth.
Read More...AI-designed mini-protein targeting claudin-5 to enhance blood–brain barrier integrity
The authors employ computational protein design to identify a mini-protein with the potential to enhance binding of the tight junction protein, claudin-5, at the blood-blood barrier with therapeutic potential for neurodegenerative diseases.
Read More...Governing Glioblastoma: A novel therapy to restore motor control and mitigate glioblastoma proliferation
The authors looked at ways that seizures in patients with glioblastoma could be treated using C. elegans as a model system.
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