Some cancer treatments lose efficacy when combined with treatments for excessive stomach acid, due to the changes in the stomach environment caused by the stomach acid treatments. Lin and Lin investigate information on oral cancer drugs to see what information is available on interactions of these drugs.
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Assessing the association between developed surface area and land surface temperature of urban areas
Almost all urban areas face the challenge of urban heat islands, areas with substantially hotter land surface temperatures than the surrounding rural areas. These areas are associated with worse air and water
quality, increased power outages, and increased heat-related illnesses. To learn more about these areas, Ustin et al. analyze satellite images of Cleveland neighborhoods to find out if there is a correlation between surface area development and surface temperature.
The Dependence of CO2 Removal Efficiency on its Injection Speed into Water
Recent research confirms that climate change, driven by CO2 emissions from burning fossil fuels, poses a significant threat to humanity. In response, authors explore methods to remove CO2 from the atmosphere, including breaking its molecular bonds through high-speed collisions.
Read More...Development of selective RAC1/KLRN inhibitors
Kalirin is a guanine nucleotide exchange factor (GEF) for the GTPase RAC1, linked to schizophrenia and Alzheimer’s Disease. It plays a crucial role in synaptic plasticity by regulating dendritic spine formation and actin cytoskeleton remodeling, which are essential for creating new synapses. Authors developed two novel compounds targeting kalirin, confirming that predictive modeling can indicate biological activity.
Read More...Mendelian randomization reveals shared genetic landscape in autism spectrum disorder and Alzheimer's disease
Autism Spectrum Disorder (ASD) and Alzheimer's Disease (AD) are distinct conditions, but research suggests a link, as individuals with ASD are 2.5 times more likely to develop AD. A study employing genome-wide association studies and Mendelian randomization revealed shared genetic factors, particularly in synaptic regulation pathways, that may increase the risk of AD in those with ASD. These findings provide insights into the genetic underpinnings connecting the two disorders.
Read More...Assessing the possibility of using entomopathogenic fungi for mosquito control in Hawaii
Fungi that attack and kill insects have promise for targeting mosquitoes without the harmful environmental impacts of chemicals like DDT. To find out whether fungi might be effective in controlling mosquitoes in Hawaii, Jiang and Chan test the effects of Hawaiian fungal isolates on mosquito larvae.
Read More...Risk factors contributing to Pennsylvania childhood asthma
Asthma is one of the most prevalent chronic conditions in the United States. But not all people experience asthma equally, with factors like healthcare access and environmental pollution impacting whether children are likely to be hospitalized for asthma's effects. Li, Li, and Ruffolo investigate what demographic and environmental factors are predictive of childhood asthma hospitalization rates across Pennsylvania.
Read More...English learner status in Florida public schools is correlated with significantly lower graduation rates
The authors explore factors affecting graduation rates of students learning English as a second language across Florida counties.
Read More...A natural language processing approach to skill identification in the job market
The authors looked at using machine learning to identify skills needed to apply for certain jobs, specifically looking at different techniques to parse apart the text. They found that Bidirectional Encoder Representation of Transforms (BERT) performed best.
Read More...An alternative to textile dyes: Synthesizing and applying PMMA nanoparticles to create structural coloration
The authors looked at developing a PMMA nanoparticle fabric dye that would be more sustainable compared to traditional fabric dyes. They were able to create PMMA based dyes in different colors that were also durable (i.e., did not fade quickly on fabric).
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