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Using Artificial Intelligence to Forecast Continuous Glucose Monitor(CGM) readings for Type One Diabetes

Jalla et al. | Aug 07, 2024

Using Artificial Intelligence to Forecast Continuous Glucose Monitor(CGM) readings for Type One Diabetes
Image credit: The authors

People with Type One diabetes often rely on Continuous Blood Glucose Monitors (CGMs) to track their blood glucose and manage their condition. Researchers are now working to help people with Type One diabetes more easily monitor their health by developing models that will future blood glucose levels based on CGM readings. Jalla and Ghanta tackle this issue by exploring the use of AI models to forecast blood glucose levels with CGM data.

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Utilizing a novel T1rho method to detect spinal degeneration via magnetic resonance imaging

Wang et al. | Oct 04, 2023

Utilizing a novel T1rho method to detect spinal degeneration via magnetic resonance imaging

Spinal degeneration has been linked to critical conditions such as osteoarthritis in adults aged 40+; while this condition is considered to be irreversible, we took interest in magnetic resonance imaging (MRI) for early detection of the condition. Ultimately, our purpose was to determine the effectiveness of a relatively novel T1rho method in the early detection of spinal degeneration, and we hypothesized that the early to mild progression of spinal degeneration would affect T1rho values following an MRI scan.

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Examining the correlation between Massa Medicata Fermentata and Crohn’s disease: Implications for treatment and patient safety

Wang et al. | Sep 15, 2025

Examining the correlation between Massa Medicata Fermentata and Crohn’s disease: Implications for treatment and patient safety

Crohn’s disease is a chronic inflammatory bowel condition with symptoms like abdominal pain, fatigue, diarrhea, and malnutrition. Though there's no cure, various treatments help manage it. This study explored the potential impact of Massa Medicata Fermentata (MMF), a fermented Chinese herbal medicine containing Saccharomyces cerevisiae, on Crohn’s disease.

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Analyzing relationships and distribution between age, sex, and eye disease at IGMCH eye OPD

Sareen et al. | Feb 20, 2025

Analyzing relationships and distribution between age, sex, and eye disease at IGMCH eye OPD
Image credit: Amanda Dalbjörn

This study analyzed patient demographics in the ophthalmology department at Indira Gandhi Medical College and Hospital (IGMCH) to assess relationships between age, sex, and eye conditions. While the overall sex distribution was equal, individual conditions varied, with cataracts and retinal disorders more common in males and conjunctival conditions slightly more prevalent in females, though none were statistically significant (p > 0.05) except for cataract patients aged 50–89 (p < 0.001). Understanding these trends can help medical facilities allocate resources more effectively for improved patient care.

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Correlation between particulate matter concentrations and COPD hospitalization rates in Massachusetts

Ganeshwaran et al. | Dec 30, 2024

Correlation between particulate matter concentrations and COPD hospitalization rates in Massachusetts
Image credit: The authors

Air pollution is thought to increase the prevalence of health conditions like chronic obstructive pulmonary disease (COPD). Ganeshwaran and Ropiak investigate this relationship by determining whether there is a correlation between between one type of air pollution (fine particulate matter concentrations) and COPD hospitalization rates in Massachusetts.

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Mendelian randomization reveals shared genetic landscape in autism spectrum disorder and Alzheimer's disease

Lee et al. | Nov 04, 2024

Mendelian randomization reveals shared genetic landscape in autism spectrum disorder and Alzheimer's disease

Autism Spectrum Disorder (ASD) and Alzheimer's Disease (AD) are distinct conditions, but research suggests a link, as individuals with ASD are 2.5 times more likely to develop AD. A study employing genome-wide association studies and Mendelian randomization revealed shared genetic factors, particularly in synaptic regulation pathways, that may increase the risk of AD in those with ASD. These findings provide insights into the genetic underpinnings connecting the two disorders.

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Risk factors contributing to Pennsylvania childhood asthma

Li et al. | Oct 30, 2024

Risk factors contributing to Pennsylvania childhood asthma
Image credit: The authors

Asthma is one of the most prevalent chronic conditions in the United States. But not all people experience asthma equally, with factors like healthcare access and environmental pollution impacting whether children are likely to be hospitalized for asthma's effects. Li, Li, and Ruffolo investigate what demographic and environmental factors are predictive of childhood asthma hospitalization rates across Pennsylvania.

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Evaluation of platelet-rich plasma vs. platelet lysate: VEGF and PDGF concentration, stability, and shelf life

Prasad et al. | Mar 30, 2022

Evaluation of platelet-rich plasma vs. platelet lysate: VEGF and PDGF concentration, stability, and shelf life

Cell-free biologicals are a novel method of treating clinical conditions which involve chronic inflammation such as tendonitis and osteoarthritis. This study compared platelet-derived growth factor (PDGF) and vascular endothelial growth factor (VEGF) in platelet-rich plasma (PRP), activated PRP (aPRP), and platelet lysate (PL). It was hypothesized that PL would contain higher concentrations of growth factors than PRP and that different storage temperatures for PL would diminish cytokine expression. Results demonstrated PL had the highest concentrations of both cytokines, with concentrations slightly diminishing at-80C. aPRP and PRP demonstrated lower concentrations of PDGF and VEGF than PL.

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Presoaking Seeds with Vinegar Improves Seed Development and Drought Tolerance in Maize Plants

D'Agate et al. | Jul 24, 2020

Presoaking Seeds with Vinegar Improves Seed Development and Drought Tolerance in Maize Plants

Climate change has contributed to the increasing annual temperatures around the world and poses a grave threat to Maize crops. Two methods proven to help combat plant drought stress effects are presoaking seeds (seeds are soaked in a liquid before planting) and the application of Acetic Acid (vinegar) to soil. The purpose of this experiment was to explore if combining these two methods by presoaking seeds with a vinegar solution can improve the seed development and plant drought tolerance of Maize plants during drought conditions.

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Investigating the Role of the Novel ESCRT-III Recruitment Factor CCDC11 in HIV Budding: A Potential Target for Antiviral Therapy

Takemaru et al. | Feb 24, 2020

Investigating the Role of the Novel ESCRT-III Recruitment Factor CCDC11 in HIV Budding: A Potential Target for Antiviral Therapy

Acquired immunodeficiency syndrome (AIDS) is a life-threatening condition caused by the human immunodeficiency virus (HIV). In this work, Takemaru et al explored the role of Coiled-Coil Domain-Containing 11 (CCDC11) in HIV-1 budding. Their results suggest that CCDC11 is critical for efficient HIV-1 budding, potentially indicating CCDC11 a viable target for antiviral therapeutics without major side effects.

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