![Disruptions in protein-protein interactions between HTT, PRPF40B, and MECP2 are involved in Lopes-Maciel-Rodan syndrome](/rails/active_storage/representations/proxy/eyJfcmFpbHMiOnsibWVzc2FnZSI6IkJBaHBBajBMIiwiZXhwIjpudWxsLCJwdXIiOiJibG9iX2lkIn19--ae2a1e4948187afbdcf0aa1470f507e7befdf765/eyJfcmFpbHMiOnsibWVzc2FnZSI6IkJBaDdCem9MWm05eWJXRjBTU0lJYW5CbkJqb0dSVlE2QzNKbGMybDZaVWtpRFRZd01IZzJNREErQmpzR1ZBPT0iLCJleHAiOm51bGwsInB1ciI6InZhcmlhdGlvbiJ9fQ==--a3b53ba1a0f83efef18f6e75a8d4ce784384bee2/Figure_5_JEI-21-180.jpg)
In an extensive study of gene mutations, and their resulting effect on protein-protein interactions, Desai and Stork found that HTT-PRPF40B-MECP2 interactions are weakened with progression of Lopes-Maciel-Rodan syndrome.
Read More...Disruptions in protein-protein interactions between HTT, PRPF40B, and MECP2 are involved in Lopes-Maciel-Rodan syndrome
In an extensive study of gene mutations, and their resulting effect on protein-protein interactions, Desai and Stork found that HTT-PRPF40B-MECP2 interactions are weakened with progression of Lopes-Maciel-Rodan syndrome.
Read More...A new hybrid cold storage material
With low-temperature transportation being critical for the progress of research and medical services by preserving biological samples and vaccines, the optimization of cold storage materials is more critical now than ever. The exclusive use of dry ice has its limitations. Notably, it proves insufficient for cold storage during long-range transportation necessary for the delivery of specimens to rural areas. In this article, the authors have proposed a new means of cold storage through the combination of dry ice and ethanol. Upon thorough analysis, the authors have determined their new method as considerably better than the use of pure dry ice across many characteristics, including cold storage capacity, longevity of material, and financial and environmental feasibility.
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Here seeking to identify a possible solution to procrastination among college students, the authors used an online experiment that involved the random assignment of study partners that they shared their study time goal with. These partners were classified by status and group membership. The authors found that status and group membership did not significantly affect the likelihood of college students achieving their committed goals, and also suggest the potential of soft commitment devices that take advantage of social relationships to reduce procrastination.
Read More...Modelling effects of alkylamines on sea salt aerosols using the Extended Aerosols and Inorganics Model
With monitoring of climate change and the evolving properties of the atmosphere more critical than ever, the authors of this study take sea salt aerosols into consideration. These sea salt aerosols, sourced from the bubbles found at the surface of the sea, serve as cloud condensation nuclei (CCN) and are effective for the formation of clouds, light scattering in the atmosphere, and cooling of the climate. With amines being involved in the process of CCN formation, the authors explore the effects of alkylamines on the properties of sea salt aerosols and their potential relevance to climate change.
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In this study, the ability of arbuscular mycorrhizal fungi to limit the growth of an agricultural weed Cirsium arvense is tested. This has important implications for developing natural herbicides.
Read More...Correlation between shutdowns and CO levels across the United States.
Concerns regarding the rapid spread of Sars-CoV2 in early 2020 led company and local governmental officials in many states to ask people to work from home and avoid leaving their homes; measures commonly referred to as shutdowns. Here, the authors investigate how shutdowns affected carbon monoxide (CO) levels in 15 US states using publicly available data. Their results suggest that CO levels decreased as a result of these measures over the course of 2020, a trend which started to reverse after shutdowns ended.
Read More...How Ethanol Concentration Affects Catalase Catalysis of Hydrogen Peroxide
Catalase is a critical enzyme in the human body because it is capable of converting potentially dangerous hydrogen peroxide into water and oxygen. This work asks whether ethanol affects catalase activity, as alcohol consumption has been often linked to hepatitis occurring in the liver, where catalase level is especially high, and ethanol is known to be capable of denaturing proteins. Testing different concentrations of ethanol found that higher concentrations reduced the activity of catalase. This work has important implications on the negative effects of ethanol on metabolism, in which catalase plays an important role, and protein function more broadly.
Read More...Colorism and the killing of unarmed African Americans by police
The purpose of this study was to investigate the relationship between colorism and police killings of unarmed African American suspects. The authors collected data from the Washington Post database, which reports unarmed African American victims from 2015–2021, and found that the victims who were killed by police were darker on average than a control population of African Americans that had not encountered the police.
Read More...Reimagize – a digital card-based roleplaying game to improve adolescent girls’ body image
Reimagize, a role-playing with decision-making, was conjured, implementing social psychological concepts like counter-stereotyping and perspective-taking. As the game works implicitly to influence body image, it even counters image issues beyond personal body dissatisfaction. This study explored whether a digital role-playing card game, incorporating some of the most common prejudices of body image (like size prejudice, prejudices from the media, etc.) as identified by a digital survey/questionnaire completed by Indian girls aged 11-21, could counter these issues and reduce personal body dissatisfaction.
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