Cellular senescence plays a key role in aging cells and is attributed to a number of disease and pathology. These authors find that genetic editing of both RPS6KB1 and PPARGC1A revitalizes a human skin fibroblast cell line.
Read More...Innovative Treatment for Reducing Senescence and Revitalizing Aging Cells through Gene Silencing
Cellular senescence plays a key role in aging cells and is attributed to a number of disease and pathology. These authors find that genetic editing of both RPS6KB1 and PPARGC1A revitalizes a human skin fibroblast cell line.
Read More...Decline in vocabulary richness in individuals with Alzheimer's disease
The authors looked at how vocabulary is impacted in Alzheimer's disease and whether it could be used a predictor of disease onset.
Read More...Predicting sickle cell vaso-occlusion by microscopic imaging and modeling
The authors use blood smears from individuals with sickle cell disease to correlate sickle cell frequency with the occurrence of vaso-occlusive crises.
Read More...Quantifying natural recovery of dopamine deficits induced by chronic stress
Here the authors investigated the natural recovery of stress-induced dopamine-related gene deficits in C. elegans by measuring the expression of cat-2 (dopamine biosynthesis) and sod-2 (oxidative stress) following exposure to starvation or hydrocortisone. They found that the reversibility of sod-2 and the expression of cat-2 were highly dependent on the type and severity of the stressor, suggesting that the body's natural ability to recover from dopamine dysfunction has biological limitations.
Read More...Examining the correlation between Massa Medicata Fermentata and Crohn’s disease: Implications for treatment and patient safety
Crohn’s disease is a chronic inflammatory bowel condition with symptoms like abdominal pain, fatigue, diarrhea, and malnutrition. Though there's no cure, various treatments help manage it. This study explored the potential impact of Massa Medicata Fermentata (MMF), a fermented Chinese herbal medicine containing Saccharomyces cerevisiae, on Crohn’s disease.
Read More...Applying machine learning to breast cancer diagnosis: A high school student’s exploration using R
The authors combine fine needle aspiration biopsy and machine learning algorithms to develop a breast cancer detection method suitable for resource-constrained regions that lack access to mammograms.
Read More...Using advanced machine learning and voice analysis features for Parkinson’s disease progression prediction
The authors looked at the ability to use audio clips to analyze the progression of Parkinson's disease.
Read More...A 1D model of ultrasound waves for diagnosing of hepatomegaly and cirrhosis
The authors created a 1D model to diagnose hepatomegaly and cirrhosis via ultrasound of the liver.
Read More...A comparative study of food labels in the United States and India: Adherence to Codex Alimentarius guidelines
This study investigated how well food labels from 280 different brands across multiple food and drink categories in India and the US adhered to recommended nutritional labeling standards as outlined by the Codex Alimentarius.
Read More...Elevated GPx4 and FSP1 expression in MG63 cells: Exploring potential links to drug resistance and ferroptosis
Current osteosarcoma (OS) treatments rely on surgery and chemotherapy, but drug resistance remains a major challenge that lowers patient survival rates. Ferroptosis, a form of regulated cell death, has shown promise in cancer therapy but is not well understood in OS. This study explores the use of Ferroptosis in OS.
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