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Cellular senescence plays a key role in aging cells and is attributed to a number of disease and pathology. These authors find that genetic editing of both RPS6KB1 and PPARGC1A revitalizes a human skin fibroblast cell line.

To address the limitations in predicting the severity of Atrial Septal Defect (ASD), here the authors utilized a fluid-filled chamber model to quantify the relationship between defect size and right atrial fluid output. The findings confirmed that larger ASD diameters result in a linear increase in fluid output, validating a cost-effective model that can improve clinical prognosis and treatment planning for heart failure risks.

The authors looked at how vocabulary is impacted in Alzheimer's disease and whether it could be used a predictor of disease onset.

The authors use blood smears from individuals with sickle cell disease to correlate sickle cell frequency with the occurrence of vaso-occlusive crises.

Here the authors investigated the natural recovery of stress-induced dopamine-related gene deficits in C. elegans by measuring the expression of cat-2 (dopamine biosynthesis) and sod-2 (oxidative stress) following exposure to starvation or hydrocortisone. They found that the reversibility of sod-2 and the expression of cat-2 were highly dependent on the type and severity of the stressor, suggesting that the body's natural ability to recover from dopamine dysfunction has biological limitations.

Crohn’s disease is a chronic inflammatory bowel condition with symptoms like abdominal pain, fatigue, diarrhea, and malnutrition. Though there's no cure, various treatments help manage it. This study explored the potential impact of Massa Medicata Fermentata (MMF), a fermented Chinese herbal medicine containing Saccharomyces cerevisiae, on Crohn’s disease.

The authors looked at public knowledge regarding suggested daily limits for sugar intake and then looked at how sugar levels vary in the same drink obtained from different sources and across different days.

The authors combine fine needle aspiration biopsy and machine learning algorithms to develop a breast cancer detection method suitable for resource-constrained regions that lack access to mammograms.

The authors looked at the ability to use audio clips to analyze the progression of Parkinson's disease.

The authors created a 1D model to diagnose hepatomegaly and cirrhosis via ultrasound of the liver.