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Near-infrared activation of environmentally-friendly gold and silver nanoparticles for unclogging arteries

Gill et al. | Sep 06, 2024

Near-infrared activation of environmentally-friendly gold and silver nanoparticles for unclogging arteries

Coronary artery disease, the leading cause of death worldwide, results from cholesterol build-up in coronary arteries, limiting blood and oxygen flow to the heart. This study investigated the use of gold and silver nanoparticles coated with aspirin and activated by near-infrared light to improve blood flow in a clogged artery model. The nanoparticles increased simulated blood flow rates, demonstrating potential as a less invasive and more targeted treatment for cardiovascular disease.

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Effect of environment factors on the expression of soluble PDE8A1 in E. coli

Jiang et al. | Oct 25, 2022

Effect of environment factors on the expression of soluble PDE8A1 in <em>E. coli</em>

PDE8, a type of phosphodiesterase (PDE), is proven to be crucial in various cellular activities and physiological activities by influencing second messenger systems. It is involved in a wide range of diseases, including Alzheimer’s disease and various heart diseases. However, there is limited information about PDE8 selective inhibitors. This work aimed to improve the solubility and yield of PDE8 in the supernatant by exploring suitable culture conditions, including temperatures and different additives.

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The Effect of Delivery Method, Speaker Demographics, and Physical Environment on the Engagement Level of Older Adults

Seides et al. | May 24, 2015

The Effect of Delivery Method, Speaker Demographics, and Physical Environment on the Engagement Level of Older Adults

With an increasing older adult population and rapid advancements in technology, it is important that senior citizens learn to use new technologies to remain active in society. A variety of factors on learning were investigated through surveys of senior citizens. Older adults preferred an interactive lesson style, which also seemed to help them retain more course material.

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Effect of Collagen Gel Structure on Fibroblast Phenotype

Grace et al. | Nov 28, 2012

Effect of Collagen Gel Structure on Fibroblast Phenotype

Environment affects the progression of life, especially at the cellular level. This study investigates multiple 3-dimensional growth environments, also known as scaffolds or hydrogels, and their effect on the growth of a type of cells called fibroblasts. These results suggest that a scaffold made of collagen and polyethylene glycol are favorable for cell growth. This research is useful for developing implantable devices to aid wound healing.

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