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Identification of microwave-related changes in tissue using an ultrasound scan

Shariff et al. | Apr 24, 2024

Identification of microwave-related changes in tissue using an ultrasound scan
Image credit: Shariff and Shariff 2024

Microwave energy (ME) is used in the medical field to denature protein structures, resulting in inactivation or destruction of abnormal cells. Identifying the extent of destruction of abnormal tissue (cancer tissue or tissue with abnormal electrical activity) is essential for accomplishing successful therapy and reducing collateral damage. Our study was an ex vivo assessment of the changes on ultrasound scans (US) in chicken tissue exposed to ME. We hypothesized that any changes in tissue structures would be recognized on the reflected ultrasound waves. Ultrasound scans of tissues change with exposure to microwaves with increasing reflection of ultrasound waves. With exposure to microwaves, surface level brightness on the ultrasound scans increases statistically significantly. The findings could be used in heat related (ME and radiofrequency) procedures where clinicians would be able to actively assess lesions in real-time. Further studies are required to assess changes in tissue during active exposure to different types of energies.

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Friend or foe: Using DNA barcoding to identify arthropods found at home

Wang et al. | Mar 14, 2022

Friend or foe: Using DNA barcoding to identify arthropods found at home

Here the authors used morphological characters and DNA barcoding to identify arthropods found within a residential house. With this method they identified their species and compared them against pests lists provided by the US government. They found that none of their identified species were considered to be pests providing evidence against the misconception that arthropods found at home are harmful to humans. They suggest that these methods could be used at larger scales to better understand and aid in mapping ecosystems.

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Trajectories Between Cigarette Smoking and Electronic Nicotine Delivery System Use Among Adults in the U.S.

Primack et al. | Apr 30, 2020

Trajectories Between Cigarette Smoking and Electronic Nicotine Delivery System Use Among Adults in the U.S.

In this study, the authors characterized the trends of cigarette use amongst people who do and don't use electronic nicotine delivery systems (or ENDS). This was done to help determine if the use of ENDS is aiding in helping smokers quit, as the data on this has been controversial. They found that use of ENDS among people either with or without previous cigarette usage were more likely to continue using cigarettes in the future. This is important information contributing to our understanding of ways to effectively (and not effectively) reduce cigarette use.

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The influence of purpose-of-use on information overload in online social networking

Agarkar et al. | Nov 01, 2022

The influence of purpose-of-use on information overload in online social networking

Here, seeking to understand the effects of social media in relation to social media fatigue and/or overload in recent years, the authors used various linear models to assess the results of a survey of 27 respondents. Their results showed that increased duration of use of social media did not necessarily lead to fatigue, suggesting that quality may be more important than quantity. They also considered the purpose of an individual's social media usage as well as their engagement behavior during the COVID-19 pandemic.

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Using explainable artificial intelligence to identify patient-specific breast cancer subtypes

Suresh et al. | Jan 12, 2024

Using explainable artificial intelligence to identify patient-specific breast cancer subtypes

Breast cancer is the most common cancer in women, with approximately 300,000 diagnosed with breast cancer in 2023. It ranks second in cancer-related deaths for women, after lung cancer with nearly 50,000 deaths. Scientists have identified important genetic mutations in genes like BRCA1 and BRCA2 that lead to the development of breast cancer, but previous studies were limited as they focused on specific populations. To overcome limitations, diverse populations and powerful statistical methods like genome-wide association studies and whole-genome sequencing are needed. Explainable artificial intelligence (XAI) can be used in oncology and breast cancer research to overcome these limitations of specificity as it can analyze datasets of diagnosed patients by providing interpretable explanations for identified patterns and predictions. This project aims to achieve technological and medicinal goals by using advanced algorithms to identify breast cancer subtypes for faster diagnoses. Multiple methods were utilized to develop an efficient algorithm. We hypothesized that an XAI approach would be best as it can assign scores to genes, specifically with a 90% success rate. To test that, we ran multiple trials utilizing XAI methods through the identification of class-specific and patient-specific key genes. We found that the study demonstrated a pipeline that combines multiple XAI techniques to identify potential biomarker genes for breast cancer with a 95% success rate.

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Examining the Accuracy of DNA Parentage Tests Using Computer Simulations and Known Pedigrees

Wang et al. | Jul 13, 2020

Examining the Accuracy of DNA Parentage Tests Using Computer Simulations and Known Pedigrees

How accurate are DNA parentage tests? In this study, the authors hypothesized that current parentage tests are reliable if the analysis involves only one or a few families of yellow perch fish Perca flavescens. Their results suggest that DNA parentage tests are reliable as long as the right methods are used, since these tests involve only one family in most cases, and that the results from parentage analyses of large populations can only be used as a reference.

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Factors Influencing Muon Flux and Lifetime: An Experimental Analysis Using Cosmic Ray Detectors

Samson et al. | May 18, 2020

Factors Influencing Muon Flux and Lifetime: An Experimental Analysis Using Cosmic Ray Detectors

Muons, one of the fundamental elementary particles, originate from the collision of cosmic rays with atmospheric particles and are also generated in particle accelerator collisions. In this study, Samson et al analyze the factors that influence muon flux and lifetime using Cosmic Ray Muon Detectors (CRMDs). Overall, the study suggests that water can be used to decrease muon flux and that scintillator orientation is a potential determinant of the volume of data collected in muon decay studies.

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