Browse Articles

The effect of bioenhancers on ampicillin-sulbactam as a treatment against A. baumannii

Balaji et al. | Sep 21, 2024

The effect of bioenhancers on ampicillin-sulbactam as a treatment against <i>A. baumannii<i>

This article explores the potential of piperine, a bioenhancer from black pepper, to improve antibiotic efficacy against antibiotic-resistant Acinetobacter baumannii. By combining piperine with ampicillin-sulbactam, the study demonstrated a significant reduction in bacterial growth for most strains tested, showcasing the promise of bioenhancers in combating resistant pathogens. This research highlights the possibility of reducing the required antibiotic dosage, potentially offering a new strategy in the fight against drug-resistant bacteria.

Read More...

Nanotexturing as a method to reduce dust accumulation on solar panels

Choi et al. | Jan 30, 2025

Nanotexturing as a method to reduce dust accumulation on solar panels

Dust accumulation on solar panels can reduce electricity output by 20–50%, posing a major challenge for solar energy collection. Instead of altering panel design, we explored a simpler approach by modifying surface energy through nanotexturing, predicting that hydrophobic surfaces would repel both water and dust. This study found that treating glass and silicone surfaces with potassium hydroxide (KOH) for 13 and 10 minutes, respectively, created optimal nanotextures (445 nm for glass, 205 nm for silicone), significantly reducing dirt accumulation and improving solar energy capture.

Read More...

Nitric Oxide Synthesis/Pathway Inhibitors in Daphnia magna Reverse Alcohol-Induced Heart Rate Decrease

Gunturi et al. | Sep 17, 2019

Nitric Oxide Synthesis/Pathway Inhibitors in Daphnia magna Reverse Alcohol-Induced Heart Rate Decrease

Chronic alcohol consumption can cause cardiac myopathy, which afflicts about 500,000 Americans annually. Gunturi et al. wanted to understand the effects of alcohol on heart rate and confirm the role of nitric oxide (NO) signaling in heart rate regulation. Using the model organism Daphnia magna, a water crustacean with a large, transparent heart, they found that the heart rate of Daphnia magna was reduced after treatment with alcohol. This depression could be reversed after treatment with inhibitors of NO synthesis and signaling. Their work has important implications for how we understand alcohol-induced effects on heart rate and potential treatments to reverse heart rate depression as a result of alcohol consumption.

Read More...

The Effect of Different Fructose Diets on the Lifespan of C. elegans

Chen et al. | May 10, 2020

The Effect of Different Fructose Diets on the Lifespan of <em>C. elegans</em>

High-fructose diets consumed widely in modern societies predisposes to metabolic diseases such as diabetes. Using the worm C. elegans, the authors of this study investigated the effect of fructose on the worm's survival rates. They found that worms fed 15% fructose had a lower life expectancy than those on a fructose-free diet. These results suggest that, like in humans, fructose has a negative effect on worm survival, which makes them an easy, attractive model to study the effects of fructose on health.

Read More...

Investigating facilitated biofilm formation in Escherichia coli exposed to sublethal levels of ampicillin

Yang et al. | Jan 20, 2023

Investigating facilitated biofilm formation in <em>Escherichia coli</em> exposed to sublethal levels of ampicillin

Here, the authors recognized the tendency of bacteria to form biofilms, where this behavior offers protection against threats such as antibiotics. To investigate this, they observed the effects of sublethal exposure of the antibiotic ampicillin on E. coli biofilm formation with an optical density crystal violet assay. They found that exposure to ampicillin resulted in the favored formation of biofilms over time, as free-floating bacteria were eradicated.

Read More...