Browse Articles

Evaluating Biomarkers and Treatments for Acute Kidney Injury in a Zebrafish Model

Mathew et al. | Aug 11, 2019

Evaluating Biomarkers and Treatments for Acute Kidney Injury in a Zebrafish Model

Coronary Artery Disease (CAD) is the leading cause of death in the United States, and 81% of Acute Kidney Injury (AKI) patients in the renal fibrosis stage later develop CAD. In this study, Mathew and Joykutty aimed to create a cost-effective strategy to treat AKI and thus prevent CAD using a model of the zebrafish, Danio rerio. They first tested whether AKI is induced in Danio rerio upon exposure to environmental toxins, then evaluated nitrotyrosine as an early biomarker for toxin-induced AKI. Finally, they evaluated 4 treatments of renal fibrosis, the last stage of AKI, and found that the compound SB431542 was the most effective treatment (reduced fibrosis by 99.97%). Their approach to treating AKI patients, and potentially prevent CAD, is economically feasible for translation into the clinic in both developing and developed countries.

Read More...

The ecological mysteries of Opheodesoma spectabilis : Seasonal trends, habitat preferences, and climate responses

Watson et al. | Jul 26, 2026

The ecological mysteries of <i>Opheodesoma spectabilis</i>	: Seasonal trends, habitat preferences, and climate responses

This study examines how environmental conditions influence the abundance and ecological role of the sea cucumber Opheodesoma spectabilis in Kāneʻohe Bay. Field observations and laboratory experiments showed that the species is more common in algae-dominated sandy habitats, where it improves water clarity and increases dissolved oxygen through bioturbation. However, exposure to very high temperatures caused rapid mortality, suggesting that marine heat waves could threaten this species and the ecological functions it provides.

Read More...

Using satellite surface temperature data to monitor urban heat island

Meister et al. | Feb 13, 2026

Using satellite surface temperature data to monitor urban heat island
Image credit: Meister, Horvath, and Brown de Colstoun

This manuscript investigates the urban heat island (UHI) effect by utilizing two satellite datasets: Landsat (high spatial resolution, lower temporal resolution) and MODIS (lower spatial resolution, high temporal resolution). The authors hypothesized that Landsat would provide better spatial detail, while MODIS would better capture temporal variations. Their analysis in the Washington D.C.–Baltimore region supports these hypotheses, demonstrating that Landsat offers finer spatial details, whereas MODIS provides more consistent seasonal patterns and better detects heatwave frequencies.

Read More...

Unit-price anchoring affects consumer purchasing behavior

James et al. | Jan 15, 2025

Unit-price anchoring affects consumer purchasing behavior

This study examines how anchoring—providing numerical suggestions like "2 for $4"—can influence consumer purchasing decisions and increase revenue. The researchers tested three types of price anchors on 29 high school students shopping in a mock store.

Read More...