Browse Articles

This study combines gene expression, mutation profiling, and survival analysis of 17 clinically important genes in breast cancer, utilizing the TCGA-BRCA dataset. Our results show that there are different patterns of oncogene upregulation, different levels of tumor suppressor activity, and complicated survival associations. TP53 was the most frequently mutated gene in this cohort. The results underscore the significance of multidimensional genomic analyses for a comprehensive understanding of breast cancer biology and its therapeutic ramifications.

The authors looked at different factors that influence specific gravity in beverages, including sweetener used, caffeine, carbonation, and sodium.

The authors describe the design and testing of new guide RNAs targeting the DMPK gene, which is responsible for myotonic dystrophy.

Pediatric asthma remains a significant health issue for Dallas students. This study examined the relationship between microclimatic parameters, vegetation, and pediatric asthma vulnerability (PAV) in urban schools.

Here, seeking to identify a possible explanation for the more frequent diagnosis of autism spectrum disorder (ASD) in males than females, they sought to investigate a potential sex bias in the expression of ASD-associated genes. Based on their analysis, they identified 17 ASD-associated candidate genes that showed stronger collective sex-dependent expression.

In this article the authors look at the lung microbiome in patients with cystic fibrosis to determine what the major bacterial species present are.

Understanding how bacteria respond to other bacteria could facilitate their ability to initiate and maintain their infectiousness. The phenomenon by which bacteria signal to each other via chemical signals is called quorum sensing, which could be targeted to deter bacterial infection in some cases if better understood. In this article, the authors study how a bacterium called V. fischeri uses quorum sensing to change bioluminescence, an easy readout that facilitates studying quorum sensing in this strain.

Here, based on identification of iron deficiencies of a majority of people around the world, the authors sought to understand how the two main forms of dietary iron, heme and non-heme, affect the bacteria found in the human gut. by using a cell plate study, they found that bacterial growth increased with increasing concentration os either form of iron, up until the point where the high iron content resulted in cytotoxicity. They suggest this evidence points to the potential dangers of overconsumption of iron.

To best identify tuberculosis and pneumonia diagnoses in chest x-rays, the authors compare different deep learning convolution neural networks.

In this article, the authors investigate the RNA expression differences between groups of chronic cocaine abusers and drug-free subjects.