Heliobacter felis causes gastritis which is accompanied by a range of unpleasant symptoms in small animals such as cats. In order to identify effective antibiotics for treating H. felis infections, the researchers investigate whether a combination of different antibiotics is more effective than the use of individual antibiotics alone. Of the antibiotics they selected, Streptomycin alone was better than any other single antibiotic or in combination. Their results have not yet been validated in live animals, but suggest that Streptomycin alone might be an effective treatment of H. felis-induced gastritis in cats.
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The Impacts of Varying Types of Light on the Growth of Five Arabidopsis Varieties
Arabadopsis, “the fruit fly of plants”, is an easy to grow plant system for genetic manipulation. Here, researchers tested the effects of varied light conditions on plants with specific mutations in the light sensing pathways.
Read More...Assessing and Improving Machine Learning Model Predictions of Polymer Glass Transition Temperatures
In this study, the authors test whether providing a larger dataset of glass transition temperatures (Tg) to train the machine-learning platform Polymer Genome would improve its accuracy. Polymer Genome is a machine learning based data-driven informatics platform for polymer property prediction and Tg is one property needed to design new polymers in silico. They found that training the model with their larger, curated dataset improved the algorithm's Tg, providing valuable improvements to this useful platform.
Read More...Potential Multifunctional Agents for Dual Therapy of Age-Related and Associated Diseases: Alzheimer’s Disease and Type 2 Diabetes Mellitus
Studies show an age-related link between Alzheimer’s Disease and Type 2 Diabetes Mellitus with oxidative stress a characteristic of both. Here, methanolic fractionations and extracts of four Ayurvedic plants were assessed for their protective abilities using a number of in vitro assays. Extracts inhibited oxidative stress and reduced activity of key enzymes involved in the pathogenesis of both diseases in neuroblastoma cells.
Read More...Developing a Portable, Reusable, and Inexpensive Magnesium-Air Fuel Cell
One of the greatest challenges we face today is the sustainable production, storage, and distribution of electrical power. One emerging technology with great promise in this area is that of metal-air fuel cells—a long-term and reusable electricity storage system made from a reactive metal anode and a saline solution. In this study the authors tested several different types of metal to determine which was the most suitable for this application. They found that a fuel cell with a magnesium anode was superior to fuel cells made from aluminum or zinc, producing a voltage and current sufficient for real-world applications such as charging a mobile phone.
Read More...The Effects of Post-Consumer Waste Polystyrene on the Rate of Mealworm Consumption
In a world where plastic waste accumulation is threatening both land and sea life, Green et al. investigate the ability of mealworms to breakdown polystyrene, a non-recyclable form of petrochemical-based polymer we use in our daily lives. They confirm that these organisms, can degrade various forms of polystyrene, even after it has been put to use in our daily lives. Although the efficiency of the degradation process still requires improvement, the good news is, the worms are tiny and themselves are biodegradable, so we can use plenty of them without worrying about space and how to get rid of them. This is very promising and certainly good news for the planet.
Read More...Understanding the Mechanism of Star-Block Copolymers as Nanoreactors for Synthesis of Well-Defined Silver Nanoparticles
Here, the authors characterize how silver ions nucleate a star-block copolymer to generate nano-sized silver particles.
Read More...The Role of Temporal Lobe Epilepsy in Cardiac Structure and Function
Cardiac autonomic and structural changes may occur in temporal lobe epilepsy patients and contribute to the risk of sudden unexpected death in epilepsy patients. Choi and colleagues reviewed clinical charts to obtain patients’ lifetime seizure count, antiepileptic drug use, and history of heart disease, followed by transthoracic echocardiogram to calculate left ventricle dimensions, ejection fraction, and left ventricle mass. By comparing epilepsy patients to control subjects, they found that epilepsy patients had thinner left ventricle walls and smaller ejection fraction, but with no significant difference in left ventricle mass.
Read More...Development of Diet-Induced Insulin Resistance in Drosophila melanogaster and Characterization of the Anti-Diabetic Effects of Resveratrol and Pterostilbene
Dhar and colleagues established a Type II diabetes mellitus (T2DM) model in fruit flies, using this model to induce insulin resistance and characterize the effects Resveratrol and Pterostilbene on a number of growth and activity metrics. Resveratrol and Pterostilbene treatment notably overturned the weight gain and glucose levels. The results of this study suggest that Drosophila can be utilized as a model organism to study T2DM and novel pharmacological treatments.
Read More...Differentiation of Waste Plastic Pyrolysis Fuels to Conventional Diesel Fuel
Plastic pollution and energy shortages are pressing issues in today’s world. The authors examined whether waste plastic pyrolysis fuels are similar to conventional diesel and, thus, a plausible alternative fuel. Results showed that waste plastic pyrolysis fuels did not match up to diesel overall, though several fuels came close in calorific value.
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