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Efficacy of natural coagulants in reducing water turbidity under future climate change scenarios

Cho et al. | Nov 13, 2024

Efficacy of natural coagulants in reducing water turbidity under future climate change scenarios
Image credit: pine watt

Here the authors investigated the effects of natural coagulants on reducing the turbidity of water samples from the Tennessee River Watershed. They found that turbidity reduction was higher at lower temperatures for eggshells. They then projected and mapped turbidity reactions under two climate change scenarios and three future time spans for eggshells. They found site-specific and time-vary turbidity reactions using natural coagulants could be useful for optimal water treatment plans.

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pH-dependent drug interactions with acid reducing agents

Lin et al. | Nov 12, 2024

pH-dependent drug interactions with acid reducing agents
Image credit: The authors

Some cancer treatments lose efficacy when combined with treatments for excessive stomach acid, due to the changes in the stomach environment caused by the stomach acid treatments. Lin and Lin investigate information on oral cancer drugs to see what information is available on interactions of these drugs.

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Development of selective RAC1/KLRN inhibitors

Kubrat Neczaj-Hruzewicz et al. | Nov 04, 2024

Development of selective RAC1/KLRN inhibitors

Kalirin is a guanine nucleotide exchange factor (GEF) for the GTPase RAC1, linked to schizophrenia and Alzheimer’s Disease. It plays a crucial role in synaptic plasticity by regulating dendritic spine formation and actin cytoskeleton remodeling, which are essential for creating new synapses. Authors developed two novel compounds targeting kalirin, confirming that predictive modeling can indicate biological activity.

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Risk factors contributing to Pennsylvania childhood asthma

Li et al. | Oct 30, 2024

Risk factors contributing to Pennsylvania childhood asthma
Image credit: The authors

Asthma is one of the most prevalent chronic conditions in the United States. But not all people experience asthma equally, with factors like healthcare access and environmental pollution impacting whether children are likely to be hospitalized for asthma's effects. Li, Li, and Ruffolo investigate what demographic and environmental factors are predictive of childhood asthma hospitalization rates across Pennsylvania.

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The correlation between bacteria and colorectal cancer

Zhang et al. | Oct 21, 2024

The correlation between bacteria and colorectal cancer

The authors looked at abundance of bacteria in stool samples from patients with colorectal cancer compared to controls. They found different bacteria that was more prevalent in patients with colorectal cancer as well as bacteria in control patients that may indicate a beneficial gut microbiome.

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Creating a drought prediction model using convolutional neural networks

Bora et al. | Oct 08, 2024

Creating a drought prediction model using convolutional neural networks
Image credit: The authors

Droughts kill over 45,000 people yearly and affect the livelihoods of 55 million others worldwide, with climate change likely to worsen these effects. However, unlike other natural disasters (hurricanes, etc.), there is no early detection system that can predict droughts far enough in advance to be useful. Bora, Caulkins, and Joycutty tackle this issue by creating a drought prediction model.

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