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Heavy Metal Contamination of Hand-Pressed Well Water in HuNan, China

Long et al. | Oct 20, 2019

Heavy Metal Contamination of Hand-Pressed Well Water in HuNan, China

Unprocessed water from hand-pressed wells is still commonly used as a source of drinking water in Chenzhou, the “Nonferrous Metal Village” of China. Long et al. conducted a study to measure the heavy metal contamination levels and potential health effects in this area. Water samples were analyzed through Inductively Coupled Plasma Optical Emission Spectroscopy (ICPOES) and the concentrations of 20 metal elements. Results showed that although none of the samples had dangerous levels of heavy metals, the concentrations of Al, Fe, and Mn in many locations substantially exceeded those suggested in the Chinese Drinking Water Standard and the maximum contaminant levels of Environmental Protection Agency (EPA). The authors have made an important discovery regarding the water safety in HuNan and their suggestions to install water treatment systems would greatly benefit the community.

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A Temperature-Based Comparison of Compounds Found in Bao Chong Tea, Green Tea, and Black Tea

Lin et al. | May 14, 2019

A Temperature-Based Comparison of Compounds Found in Bao Chong Tea, Green Tea, and Black Tea

While tea has a complex history, recently the health benefits of this beverage have come into focus. In this study, researchers sought to compare the levels of caffeine, catechins and L-theanine between different types of tea using NMR spectroscopy. Further, the impact of brewing temperature on the release of these compounds was also assessed. Of those tested, Bao Chong tea had the highest levels of these compounds. Brewing temperatures between 45ºC and 75ºC were found to be optimal for compound release. These results can help consumers make informed choices about their tea preparation and intake.

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Assessing the Efficacy of NOX Enzyme Inhibitors as Potential Treatments for Ischemic Stroke in silico

Vinay et al. | Sep 18, 2020

Assessing the Efficacy of NOX Enzyme Inhibitors as Potential Treatments for Ischemic Stroke <i>in silico</i>

Ischemic stroke occurs when blood flow to the brain is interrupted, causing brain damage. This study investigated the effectiveness of different NOX inhibitors as treatments for ischemic stroke in silico. The results help corroborate previous in vivo and in vitro studies in an in silico format, and can be used towards developing drugs to treat ischemic stroke.

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Effect of heme vs. non-heme iron supplements on gut microbiome fitness

Dogra et al. | Nov 07, 2022

Effect of heme vs. non-heme iron supplements on gut microbiome fitness

Here, based on identification of iron deficiencies of a majority of people around the world, the authors sought to understand how the two main forms of dietary iron, heme and non-heme, affect the bacteria found in the human gut. by using a cell plate study, they found that bacterial growth increased with increasing concentration os either form of iron, up until the point where the high iron content resulted in cytotoxicity. They suggest this evidence points to the potential dangers of overconsumption of iron.

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Comparing the Biodegradability of Petroleum-based Plastic with a Novel, Sustainable Bio-plastic Alternative

Van Note et al. | Dec 02, 2020

Comparing the Biodegradability of Petroleum-based Plastic with a Novel, Sustainable Bio-plastic Alternative

In this research, a novel bioplastic inclusive of bamboo tannins and chitosan is selected from more than 60 trial formula variations based on resulting strength, fatigue, and transparency attributes. The biodegradability of the finalized bioplastic is compared to that of conventional polyethylene, in addition to investigating its solubility and water absorbance. This research displays the potential of a legitimate, fully biodegradable plastic alternative to current marketplace bioplastics.

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Ground-based Follow-up Observations of TESS Exoplanet Candidates

Tang et al. | May 29, 2020

Ground-based Follow-up Observations of  TESS Exoplanet Candidates

The goal of this study was to further confirm, characterize, and classify LHS 3844 b, an exoplanet detected by the Transiting Exoplanet Survey Satellite (TESS). Additionally, we strove to determine the likeliness of LHS 3844 b and similar planets as qualified candidates for observation with the James Webb Space Telescope (JWST).

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Comparative singlet oxygen photosensitizer efficiency of berberine, rose bengal, and methylene blue by time course nuclear magnetic resonance (NMR) monitoring of a photochemical 4+2 cycloaddition endoperoxide formation

Su et al. | May 14, 2021

Comparative singlet oxygen photosensitizer efficiency of berberine, rose bengal, and methylene blue by time course nuclear magnetic resonance (NMR) monitoring of a photochemical 4+2 cycloaddition endoperoxide formation

Berberine, a natural product alkaloid, has been shown to exert biological activity via in situ production of singlet oxygen when photo irradiated. Berberine utilizes singlet oxygen in its putative mechanism of action, wherein it forms an activated complex with DNA and photosensitizes triplet oxygen to singlet oxygen to specifically oxidize guanine residues, thereby halting cell replication and leading to cell death. This has potential application in photodynamic therapy, alongside other such compounds which also act as photosensitizers and produce singlet oxygen in situ. The quantification of singlet oxygen in various photosensitizers, including berberine, is essential for determining their photosensitizer efficiencies. We postulated that the singlet oxygen produced by photoirradiation of berberine would be superior in terms of singlet oxygen production to the aforementioned photosensitizers when irradiated with UV light, but inferior under visible light conditions, due to its strong absorbance of UV wavelengths.

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