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Effect of hypervitaminosis A in regenerating planaria: A potential model for teratogenicity testing

Bennet et al. | Dec 12, 2022

Effect of hypervitaminosis A in regenerating planaria: A potential model for teratogenicity testing

This unique research study evaluated the potential use of the flatworm, brown planaria (Dugesia tigrine), as an alternative model for teratogenicity testing. In this study, we exposed amputated planaria to varying concentrations of a known teratogen, vitamin A (retinol), for approximately 2 weeks, and evaluated multiple parameters including the formation of blastema and eyes. The results from this study demonstrated that high concentrations of retinol caused defects in head and eye formation in regenerating planaria, with similarities to vitamin A related teratogenicity findings in mammals. Based on these results, regenerating brown planaria are a promising alternative model for teratogenicity testing, which can potentially be paradigm shifting as it can reduce cost, time, and pregnant animal use in research.

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Trajectories Between Cigarette Smoking and Electronic Nicotine Delivery System Use Among Adults in the U.S.

Primack et al. | Apr 30, 2020

Trajectories Between Cigarette Smoking and Electronic Nicotine Delivery System Use Among Adults in the U.S.

In this study, the authors characterized the trends of cigarette use amongst people who do and don't use electronic nicotine delivery systems (or ENDS). This was done to help determine if the use of ENDS is aiding in helping smokers quit, as the data on this has been controversial. They found that use of ENDS among people either with or without previous cigarette usage were more likely to continue using cigarettes in the future. This is important information contributing to our understanding of ways to effectively (and not effectively) reduce cigarette use.

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Exploring differences in men’s marijuana consumption and cigarette smoking by race and citizenship status

Miriyala et al. | Sep 04, 2024

Exploring differences in men’s marijuana consumption and cigarette smoking by race and citizenship status

This study examined the relationship between citizenship status, racial background, and the use of marijuana and cigarettes among males in California using data from the 2017–2018 California Health Interview Survey. Findings indicated that non-citizens and naturalized citizens were less likely to use marijuana compared to US-born citizens, while Asian and Latino males were less likely to consume marijuana than White males. Additionally, various racial groups were more likely to smoke cigarettes compared to White males, suggesting that targeted health interventions based on citizenship status and race could be beneficial.

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Antibacterial activity by Dombeya wallichii plant extracts obtained by ultrasound-assisted extraction

Herur et al. | Nov 13, 2023

Antibacterial activity by <em>Dombeya wallichii</em> plant extracts obtained by ultrasound-assisted extraction

Medicinal plants could be a good source of medication to combat antibiotic resistance. Dombeya wallichii, which is commonly called Pink Ball Tree in the family Sterculiaceae, has been documented to have medicinal potential. We observed the highest antibacterial activity in the stem extracts, followed by leaf and bark extracts. The extracts were more effective against tested Gram-positive bacteria when compared with Gram-negative strains.

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FRUGGIE – A Board Game to Combat Obesity by Promoting Healthy Eating Habits in Young Children

Huprikar et al. | Jun 13, 2018

FRUGGIE – A Board Game to Combat Obesity by Promoting Healthy Eating Habits in Young Children

The authors created a board game to teach young children about healthy eating habits to see whether an interactive and family-oriented method would be effective at introducing and maintaining a love for fruits and veggies. Results showed that children developed a liking for fruits and vegetables, and none regressed. Half maintained their level of enjoyment for fruits and vegetables during the research period, while the other half had a positive increase. The results show that a simple interactive game can shape how young children relate to food and encourage them to maintain healthy habits.

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