The authors looked at the ability of berberine in combination with melatonin to have anticancer effects when tested in an in vitro cell model.
Read More...Novel anticancer effects of melatonin and berberine via signaling pathways in colorectal cancer and lymphoma
The authors looked at the ability of berberine in combination with melatonin to have anticancer effects when tested in an in vitro cell model.
Read More...The effects of dysregulated ion channels and vasoconstriction in glioblastoma multiforme
Incorporating graphite from pencils as a component of lithium-ion batteries
The authors looked at the ability to use graphite from pencils in anodes of lithium-anode batteries.
Read More...Citrate and lactate drive glioblastoma progression via activation of tumor-associated macrophages
The authors looked at the impact of citrate and lactate on glioblastoma progression. Their results provide important insights for future immunotherapies aimed at treating glioblastoma.
Read More...Designing gRNAs to reduce the expression of the DMPK gene in patients with classic myotonic dystrophy
The authors describe the design and testing of new guide RNAs targeting the DMPK gene, which is responsible for myotonic dystrophy.
Read More...Computational Study of Erosion Effects on a Triangular Aerofoil's Aerodynamics at Reynolds number of 10,000
This study examined the impact of erosion on the performance of a triangular aerofoil at a low Reynolds number (Re = 10,000), relevant for harsh conditions like those on Mars.
Read More...Recombinant preparation and characterization of ADH1C and ALDH2 in alcohol metabolism
The authors test the activity of two purified human alcohol detoxification enzymes, alcohol dehydrogenase and aldehyde dehydrogenase.
Read More...The design of Benzimidazole derivatives to bind to GDP-bound K-RAS for targeted cancer therapy
In this study, the authors looked at a proto-oncogene, KRAS, and searched for molecules that are predicted to be able to bind to the inactive form of KRAS. They found that a modified version of Irbesartan, a derivative of benzimidazole, showed the best binding to inactive KRAS.
Read More...Surface cleanliness of hydrothermally grown zinc oxide microparticles compared to commercial nanoparticles
The authors test the usefulness of zinc oxide microparticles relative to zinc oxide nanoparticles as antibacterial agents.
Read More...DNA repair protein mutations alter blood cancer sensitivity to cisplatin or gemcitabine in vitro
The authors investigate whether human blood cancers carrying mutations in DNA repair genes possess increased sensitivity to common chemotherapy drugs cisplatin or gemcitabine.
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