One important factor that contributes to human cancers is accumulated damage to cells' DNA due to the oxidative stress caused by free radicals. In this study, the authors investigate the effects of several different tea leaf extracts on oxidative stress in cultured human prostate cells to see if antioxidants in the tea leaves could help protect cells from this type of DNA damage. They found that all four types of tea extract (as well as direct application of the antioxidant EGCG) improved the outcomes for the cultured cells, with white tea extract having the strongest effect. This research suggests that tea extracts and the antioxidants that they contain may have applications in the treatment of the many diseases associated with cellular DNA damage, including cancer.
Read More...Browse Articles
The design of Benzimidazole derivatives to bind to GDP-bound K-RAS for targeted cancer therapy
In this study, the authors looked at a proto-oncogene, KRAS, and searched for molecules that are predicted to be able to bind to the inactive form of KRAS. They found that a modified version of Irbesartan, a derivative of benzimidazole, showed the best binding to inactive KRAS.
Read More...A comparison study in the expansion of human bone marrow mesenchymal stem cells
In this study, the effects of different sources of serum on growing mesenchymal stem cells are compared with the goal of identifying one more suitable for clinical use.
Read More...Distribution of prophages in the Streptococcus bacteria genus and their role in increasing host pathogenicity
The authors investigated prophages present in Streptococcus bacteria that may increase their survival in different environments.
Read More...Cathodal Galvanotaxis: The Effect of Voltage on the distribution of Tetrahymena pyriformis
The surface of the unicellular eukaryote, Tetrahymena pyriformis, is covered with thousands of hair-like cilia. These cilia are very similar to cilia of the human olfactory and respiratory tracts making them model organisms for studying cilia function and pathology. The authors of this study investigated the effect of voltage on T. pyriformis galvanotaxis, the movement towards an electrical stimulus. They observed galvanotaxis towards the cathode at voltages over 4V which plateau, indicating opening of voltage gated-ion channels to trigger movement.
Read More...Changing electronic use behavior in adolescents while studying: An interventional psychology experiment
Here, the authors investigated the effects of an interventional psychology on the study habits of high school students specifically related to the use of electronic distractions such as social media or texting, listening to music, or watching TV. They reported varying degrees of success between the control and intervention groups, suggesting that the methods of habit-breaking for students merits further study.
Read More...Floor level estimation using MEMS pressure sensors
The authors propose a method to help first responders find the location of a person within a high-rise building in densely populated areas.
Read More...Observing effects of resolving leaky gut on sugar, fat, and insulin levels during type 1 diabetes in fruit flies
This study uses a fruit fly model of type 1 diabetes (T1D) to determine whether strengthening intestinal tight junctions to reduce intestinal permeability would improve T1D symptoms.
Read More...Characterizing Quorum Sensing-Induced Bioluminescence in Variable Volumes With Vibrio fischeri Using Computer Processing Methods
Understanding how bacteria respond to other bacteria could facilitate their ability to initiate and maintain their infectiousness. The phenomenon by which bacteria signal to each other via chemical signals is called quorum sensing, which could be targeted to deter bacterial infection in some cases if better understood. In this article, the authors study how a bacterium called V. fischeri uses quorum sensing to change bioluminescence, an easy readout that facilitates studying quorum sensing in this strain.
Read More...Exploring the possibilities for reactions between SiW and alkaline solutions to be renewable energy sources
The authors looked at hydrogen gas production and how reaction temperature, concentration and alkaline solution used impacted the overall reaction with silicon. They found that all alkaline solutions tested would be viable options for using silicon waste to produce hydrogen gas to be used a renewable energy source.
Read More...