Browse Articles

The Effect of Ethanol Concentration on Beta-Cell Development in Zebrafish

Payne et al. | Jan 15, 2014

The Effect of Ethanol Concentration on Beta-Cell Development in Zebrafish

Alcohol is known to cause various developmental diseases including Fetal Alcohol Syndrome. Here the authors investigate the effect of ethanol on the development of zebrafish beta cells, the part of the pancreas associated with Type 1 Diabetes. They find that exposure to ethanol does adversely affect beta-cell development, suggesting that alcohol ingestion during pregnancy may be linked to diabetes in newborns.

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Impacts of the gut microbiota on arginine synthesis

Lane et al. | Aug 15, 2024

Impacts of the gut microbiota on arginine synthesis

In this article the authors looked at arginine synthesis across different bacteria commonly found in different regional diets. They found that B. megaterium and C. sporogenes both caused a higher pH to occur on their agar plates compared to other bacteria tested indicating a greater amount of arginine synthesis.

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Unveiling the wound healing potential of umbilical cord derived conditioned medium: an in vitro study

Vasal et al. | Jun 17, 2024

Unveiling the wound healing potential of umbilical cord derived conditioned medium: an <em>in vitro</em> study

Chronic wounds pose a serious threat to an individual’s health and quality of life. However, due to the severity and morbidity of such wounds, many pre-existing treatments are inefficient or costly. While the use of skin grafts and other such biological constructs in chronic wound healing has already been characterized, the use of umbilical cord tissue has only recently garnered interest, despite the cytokine-rich composition of Wharton’s jelly (cord component). Our current study aimed to characterize the use of an umbilical cord derived conditioned medium (UC-CM) to treat chronic wounds.

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Using machine learning to develop a global coral bleaching predictor

Madireddy et al. | Feb 21, 2023

Using machine learning to develop a global coral bleaching predictor
Image credit: Madireddy, Bosch, and McCalla

Coral bleaching is a fatal process that reduces coral diversity, leads to habitat loss for marine organisms, and is a symptom of climate change. This process occurs when corals expel their symbiotic dinoflagellates, algae that photosynthesize within coral tissue providing corals with glucose. Restoration efforts have attempted to repair damaged reefs; however, there are over 360,000 square miles of coral reefs worldwide, making it challenging to target conservation efforts. Thus, predicting the likelihood of bleaching in a certain region would make it easier to allocate resources for conservation efforts. We developed a machine learning model to predict global locations at risk for coral bleaching. Data obtained from the Biological and Chemical Oceanography Data Management Office consisted of various coral bleaching events and the parameters under which the bleaching occurred. Sea surface temperature, sea surface temperature anomalies, longitude, latitude, and coral depth below the surface were the features found to be most correlated to coral bleaching. Thirty-nine machine learning models were tested to determine which one most accurately used the parameters of interest to predict the percentage of corals that would be bleached. A random forest regressor model with an R-squared value of 0.25 and a root mean squared error value of 7.91 was determined to be the best model for predicting coral bleaching. In the end, the random model had a 96% accuracy in predicting the percentage of corals that would be bleached. This prediction system can make it easier for researchers and conservationists to identify coral bleaching hotspots and properly allocate resources to prevent or mitigate bleaching events.

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Antibacterial properties of household spices and toothpaste against oral bacteria

Toliver et al. | Apr 24, 2023

Antibacterial properties of household spices and toothpaste against oral bacteria

Bacteria cause tooth decay, plaque, bad breath, and other diseases. Despite being cleaned with water and toothpaste, oral bacteria live on our toothbrushes. Bacterial growth has been shown to be inhibited by different toothpastes and common household spices. This study tested how different toothpastes and common household spices, including cinnamon, cumin, nutmeg, and ground white pepper, can inhibit bacteria from growing on toothbrushes

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The Prevalence of Brain-Eating Roundworm Baylisascaris procyonis in Merrick County, Nebraska

Reeves et al. | Sep 20, 2018

The Prevalence of Brain-Eating Roundworm <i>Baylisascaris procyonis</i> in Merrick County, Nebraska

The authors investigated an important parasite-host relationship between the raccoon roundworm and the raccoon to understand how parasite prevalence is affected by location. They found that the parasite infection was more prevalent in raccoons found closer to human dwellings, though the number of roundworm eggs was not significantly different. These results are important human health, since roundworm infection is lethal to humans and can be transmitted from raccoons to humans - the authors suggest that more research into this parasite and awareness of its prevalence is needed to prevent disease.

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