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FBS is an important component in in vitro cell culture work, helping to provide needed nutrients to cells to grow. The authors look at the ability of an alternative to FBS to support cell growth in culture.

Here the authors performed a comparative analysis to investigate the viability of using PLAY® instead of fetal bovine serum (FBS) as a growth medium to culture cells with an enzyme-linked immunosorbent assay.

Chronic wounds pose a serious threat to an individual’s health and quality of life. However, due to the severity and morbidity of such wounds, many pre-existing treatments are inefficient or costly. While the use of skin grafts and other such biological constructs in chronic wound healing has already been characterized, the use of umbilical cord tissue has only recently garnered interest, despite the cytokine-rich composition of Wharton’s jelly (cord component). Our current study aimed to characterize the use of an umbilical cord derived conditioned medium (UC-CM) to treat chronic wounds.

In this study, the effects of different sources of serum on growing mesenchymal stem cells are compared with the goal of identifying one more suitable for clinical use.